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The impact of pH on proteolytic activity in wound fluid: Implications for acid therapy

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110723Source: DataRank Database

The impact of pH on proteolytic activity in wound fluid: Implications for acid therapy is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)Impact (FWCI 2.55)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Meredith J. Crane ORCID,Lawrence Liu ORCID,Danielle Gelsinger,Alexander R. D. Jordon,Phuong Le

Live enrichment

PubMed:40962052 PMC:PMC12550788 OpenAlex:https://openalex.org/W4414246189

National Institute of Biomedical Imaging and Bioengineering

Grant: R21EB028485

National Cancer Institute Division of Cancer Prevention

Grant: R21CA256460

National Heart Lung and Blood Institute Division of Intramural Research

Grant: 3R01HL126887-02S1

NHLBI NIH HHS

Grant: R01 HL126887

National Institutes of Health

National Heart, Lung, and Blood Institute

Defense Advanced Research Projects Agency

FWCI

2.55

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)02575-X/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)02575-X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S002192582502575X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S002192582502575X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.110723

Fields of Study

Diabetic Foot Ulcer Assessment and ManagementWound Healing and TreatmentsPressure Ulcer Prevention and ManagementAnimalsHydrogen-Ion ConcentrationWound HealingMiceHumansProteolysisCathepsin DWounds and InjuriesBody FluidsPeptidesMice, Inbred C57BLMale

MeSH Terms

AnimalsBody FluidsCathepsin DHumansHydrogen-Ion ConcentrationMaleMice, Inbred C57BLPeptidesWound HealingWounds and InjuriesMiceProteolysis

Keywords

ProteasesCathepsinWound healingProteaseExtracellular matrixProteolytic enzymesExtracellularCitric acidProteolysisMatrix metalloproteinaseFluorogenic SubstrateProteolytic ActivityAcid TreatmentWound FluidAspartic Acid ProteasePepstatinMsp-ms

The impact of pH on proteolytic activity in wound fluid: Implications for acid therapy

FAIR Checklist

Authors (12)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)