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GRK phosphorylation drives β-arrestin–independent internalization of chemokine receptor CXCR5

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111114Source: DataRank Database

GRK phosphorylation drives β-arrestin–independent internalization of chemokine receptor CXCR5 is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)Impact (FWCI 0.00)OA: goldTopics (25)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Ya Zhuo ORCID,Aaren R Manz,Julia Drube ORCID,Stefan Schulz ORCID,Carsten Hoffmann ORCID

Live enrichment

PubMed:41475547 PMC:PMC12859505 OpenAlex:https://openalex.org/W7117450225

National Institute of General Medical Sciences

Grant: R35GM149253

National Institutes of Health

FWCI

0.00

Citation Percentile

0.5%

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2025.111114

publisherhttps://doi.org/10.1016/j.jbc.2025.111114

publisherhttps://api.elsevier.com/content/article/PII:S0021925825029667?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825029667?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41475547

Fields of Study

Receptor Mechanisms and SignalingChemokine receptors and signalingProtein Kinase Regulation and GTPase Signaling

MeSH Terms

beta-ArrestinsEndocytosisHumansPhosphorylationReceptors, CXCR5Chemokine CXCL13G-Protein-Coupled Receptor KinasesG-Protein-Coupled Receptor Kinase 2G-Protein-Coupled Receptor Kinase 5HEK293 Cells

Keywords

InternalizationG protein-coupled receptor kinaseCXCR5C-C chemokine receptor type 6PhosphorylationHEK 293 cellsXCL2Chemokine receptorDesensitizationArrestinBretGrk