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Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111127Source: DataRank Database

Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 0.49)OA: goldTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

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Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (19)

Anish Sen-Majumdar,J. Li ORCID,Srijon Sarkar,Tenzin Passang,Sonia Mecorapaj

Live enrichment

PubMed:41478571 PMC:PMC13080581 OpenAlex:https://openalex.org/W7117733524

National Cancer Institute

Grant: P30CA138292

Emory University Winship Cancer Institute

National Institutes of Health

Georgia Research Alliance

FWCI

0.49

Citation Percentile

0.7%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)02979-5/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)02979-5/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825029795?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825029795?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.111127

Fields of Study

Neuropeptides and Animal PhysiologyAntimicrobial Peptides and ActivitiesCoagulation, Bradykinin, Polyphosphates, and AngioedemaAnimalsHumansMiceVasoactive Intestinal PeptideReceptors, Vasoactive Intestinal Polypeptide, Type IMice, Inbred C57BLCell Line, TumorCell ProliferationReceptors, Vasoactive Intestinal Peptide, Type IIAntineoplastic AgentsReceptors, Vasoactive Intestinal PeptideLeukemia, Myeloid, AcuteT-LymphocytesLymphocyte ActivationMolecular Docking SimulationPeptides

MeSH Terms

AnimalsAntineoplastic AgentsHumansLymphocyte ActivationMice, Inbred C57BLPeptidesT-LymphocytesVasoactive Intestinal PeptideLeukemia, Myeloid, AcuteReceptors, Vasoactive Intestinal PeptideCell Line, TumorCell ProliferationReceptors, Vasoactive Intestinal Polypeptide, Type IReceptors, Vasoactive Intestinal Peptide, Type IIMiceMolecular Docking Simulation

Keywords

In silicoReceptorVasoactive intestinal peptideIn vitroPeptideIn vivoAntagonistT cellCell cultureAcute myeloid leukemiaVasoactive intestinal polypeptideAnti-cancer drugImmune ActivationProtein ModelingPeptide AntagonistAlpha Fold

Sustainable Development Goals

SDG 0: Good health and well-being

Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity

FAIR Checklist

Authors (19)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)