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Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assay

Journal of Chromatography B(2025)10.1016/j.jchromb.2025.124833Source: DataRank Database

Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assay is a research paper published in Journal of Chromatography B (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 0.00)OA: greenTopics (41)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Robynne Ashe,Alexander Duncan ORCID,Ethan C. Wilner,Keith T. Schmidt ORCID,Kristbjorn O. Gudmundsson ORCID

Live enrichment

PubMed:41878958 OpenAlex:https://openalex.org/W4415406945

Center for Cancer Research

Grant: ZIC SC 006537

NCI NIH HHS

Grant: R01 CA250469

Intramural NIH HHS

Grant: Z01 SC006536

Intramural NIH HHS

Grant: Z99 CA999999

National Institutes of Health National Cancer Institute

FWCI

0.00

Citation Percentile

0.3%

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13015840/

publisherhttps://api.elsevier.com/content/article/PII:S1570023225003873?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1570023225003873?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jchromb.2025.124833

Fields of Study

Folate and B Vitamins ResearchBiochemical and Molecular ResearchMetabolism and Genetic DisordersMedicineChemistryAnimalsTandem Mass SpectrometryChromatography, High Pressure LiquidMicePyrimidinesReproducibility of ResultsFolic Acid AntagonistsLinear ModelsLimit of DetectionPyrrolesDrug StabilityMale

MeSH Terms

AnimalsChromatography, High Pressure LiquidDrug StabilityFolic Acid AntagonistsMalePyrimidinesPyrrolesReproducibility of ResultsLinear ModelsMiceTandem Mass SpectrometryLimit of Detection

Keywords

Protein precipitationAnalyteFormic acidPharmacokineticsSelected reaction monitoringMass spectrometryElectrospray ionizationCalibration curvepreclinical studyUhplcAntifolatesBioanalytical Method