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Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naïve Adult Crohn’s Disease Patients

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.02.005Source: DataRank Database

Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naïve Adult Crohn’s Disease Patients is a research paper published in Cellular and Molecular Gastroenterology and Hepatology (2022). On theSindex it has a DataRank of 0. It has been cited 58 times.

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Enrichment:Funding (17 grants)OA: goldTopics (31)IDs (PubMed, PMC)Annotations (3)SDGs (1)

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Authors (21)

Meaghan M. Kennedy Ng ORCID,Sean V. Connelly ORCID,Manvendra Singh ORCID,Matthew R. Schaner ORCID,Michael T. Shanahan ORCID

Live enrichment

PubMed:35158099 PMC:PMC9046244

NIDDK NIH HHS

Grant: P30 DK034987

NIGMS NIH HHS

Grant: T32 GM122741

NIDDK NIH HHS

Grant: P01 DK094779

NIDDK NIH HHS

Grant: R01 DK104828

NCI NIH HHS

Grant: P30 CA016086

NIGMS NIH HHS

Grant: R35 GM122550

National Institutes of Health

Grant: 1R01DK104828-01A1

Integrative Genetic and Genomic Analyses in the Inflammatory Bowel Disease

National Institutes of Health

Grant: 3P30CA016086-42S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5P30DK034987-28

Administrative Core and Enrichment Program

National Institutes of Health

Grant: 5R35GM122550-05

Genomic and physiological impact of transposable elements

National Institutes of Health

Grant: 1ZIADK013039-04

Molecular modeling of soluble proteins

National Institutes of Health

Grant: 3P01DK094779-04S1

Host innate immune-microbial interactions and intestinal inflammation

National Institutes of Health

Grant: 5T32GM122741-05

Enhancement Training for the Next Generation of Translational Ph.D. Scientists

NCI

NIDDK

NIH

Leona M and Harry B Helmsley Charitable Trust

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.jcmgh.2022.02.005

publisherhttps://api.elsevier.com/content/article/PII:S2352345X22000327?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2352345X22000327?httpAccept=text/plain

repositoryhttps://doaj.org/article/f26eceddd75d46159db62af17e2aa45c

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9046244

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Paneth CellsEpitheliumHumansCrohn DiseaseDNA Transposable ElementsAdultGenome-Wide Association StudySingle-Cell Analysis

Keywords

EpitheliumTransposable elementGene ExpressionGenome-wide Association StudyCrohn’s DiseaseColonocyteSingle-cellLgr5IscSpibBest4AdultPaneth CellsRC799-869Diseases of the digestive system. GastroenterologyCrohn DiseaseDNA Transposable ElementsHumansSingle-Cell AnalysisOriginal Research

Sustainable Development Goals

SDG 3: 3. Good health