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Loss of Intestinal Endosome-associated Protein Sorting Nexin 27 Disrupts Epithelial Barrier and Promotes Inflammation

Cellular and Molecular Gastroenterology and Hepatology(2025)10.1016/j.jcmgh.2025.101682Source: DataRank Database

Loss of Intestinal Endosome-associated Protein Sorting Nexin 27 Disrupts Epithelial Barrier and Promotes Inflammation is a research paper published in Cellular and Molecular Gastroenterology and Hepatology (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (7 grants)Impact (FWCI 0.74)OA: goldTopics (46)IDs (PubMed, OpenAlex)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Yongguo Zhang ORCID,Yu An ORCID,Yinglin Xia ORCID,Jun Sun ORCID,Shreya Deb ORCID

Live enrichment

PubMed:41260570 OpenAlex:https://openalex.org/W4416405565

Congressionally Directed Medical Research Programs

Grant: BC191198

U.S. Department of Veterans Affairs

Grant: VA I01BX004824-06

Crohn's and Colitis Foundation of America

Grant: 902766

National Institutes of Health

Grant: R01 DK134343

National Institutes of Health

Grant: R01 DK114126

BLRD VA

Grant: I01 BX004824

NIDDK NIH HHS

Grant: R01 DK105118

FWCI

0.74

Citation Percentile

0.7%

Citation Trend

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.jcmgh.2025.101682

publisherhttps://doi.org/10.1016/j.jcmgh.2025.101682

publisherhttps://api.elsevier.com/content/article/PII:S2352345X25002231?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2352345X25002231?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41260570

Fields of Study

Barrier Structure and Function StudiesCellular transport and secretionConnexins and lens biologyAnimalsSorting NexinsHumansMiceIntestinal MucosaDextran SulfateDisease Models, AnimalInflammatory Bowel DiseasesColitisColitis, UlcerativeMice, Inbred C57BL

MeSH Terms

AnimalsColitisColitis, UlcerativeDisease Models, AnimalHumansIntestinal MucosaMice, Inbred C57BLInflammatory Bowel DiseasesDextran SulfateMiceSorting Nexins

Keywords

Sorting nexinDownregulation and upregulationInflammationSortingIntestinal mucosaAdherens JunctionsB-cateninBarrier FunctionClaudin 10E-cateninEndocytic RecyclingGoblet CellsInflammatory Bowel DiseaseMicrobiomeMuc2Paneth CellsSNX27Single-cell RNA SequencingTight JunctionsZO-1ZO-2