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MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance

Journal of Investigative Dermatology(2020)10.1016/j.jid.2020.06.038Source: DataRank Database

MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance is a research paper published in Journal of Investigative Dermatology (2020). On theSindex it has a DataRank of 0. It has been cited 33 times.

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Enrichment:Funding (13 grants)OA: greenTopics (41)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Authors (14)

Anupama Sahoo ORCID,Junko Sawada ORCID,John Marchica ORCID,Sanjay Sahoo,Fabiana Izidro Layng ORCID

Live enrichment

PubMed:32888955 PMC:PMC9004592

National Cancer Institute

Grant: P30 CA006973

National Cancer Institute

Grant: 5P30CA030199

National Institutes of Health

Grant: R21CA202197

National Institutes of Health

Grant: CA165184

NCI NIH HHS

Grant: R03 CA172847

NCI NIH HHS

Grant: R03 CA165184

NCI NIH HHS

Grant: P30 CA030199

National Institutes of Health

Grant: 5R21CA202197-02

Identification of the molecular mechanism of miR-211 and its target genes in melanocytes and pigmented melanoma senescence and apoptosis

National Institutes of Health

Grant: 3P30CA006973-53S2

Regional Oncology Research Center

National Institutes of Health

Grant: 5P30CA030199-37

Cancer Center Support Grant (CCSG)

Florida Department of Health

Johns Hopkins University

Sidney Kimmel Comprehensive Cancer Center

greenLicense: Elsevier Non-Commercial

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9004592

publisherhttps://api.elsevier.com/content/article/PII:S0022202X20320431?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022202X20320431?httpAccept=text/plain

https://doi.org/10.1016/j.jid.2020.06.038

https://pubmed.ncbi.nlm.nih.gov/32888955

MeSH Terms

Cell Line, TumorAnimalsHumansMiceMelanomaAzetidinesPiperidinesProto-Oncogene Proteins B-rafMitogen-Activated Protein Kinase 7MicroRNAsProtein Kinase InhibitorsXenograft Model Antitumor AssaysCell ProliferationMAP Kinase Signaling SystemPhosphorylationDrug Resistance, NeoplasmMutationDual Specificity Phosphatase 6Gene Knockdown TechniquesVemurafenib

Keywords

Proto-Oncogene Proteins B-rafMAP Kinase Signaling System610Xenograft Model Antitumor AssaysMiceMicroRNAsPiperidinesVemurafenibDrug Resistance, NeoplasmDual Specificity Phosphatase 6Cell Line, TumorGene Knockdown TechniquesMutationAnimalsAzetidinesHumansPhosphorylationMelanomaProtein Kinase InhibitorsMitogen-Activated Protein Kinase 7Cell Proliferation

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656171.v1figshare

Additional file 1 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656171figshare

Additional file 2 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656174.v1figshare

Additional file 2 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656174figshare

Additional file 4 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656180.v1figshare

Additional file 3 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656177.v1figshare

Additional file 3 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656177figshare

Additional file 4 of miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4

10.6084/m9.figshare.26656180figshare

MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance

FAIR Checklist

Authors (14)

Funding (13 grants)

Open Access

Topics

Linked Datasets (8)

Annotations (Europe PMC)