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Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis

Journal of Investigative Dermatology(2020)10.1016/j.jid.2020.07.011Source: DataRank Database

Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis is a research paper published in Journal of Investigative Dermatology (2020). On theSindex it has a DataRank of 0. It has been cited 46 times.

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Open Access46 citations

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Enrichment:Funding (2 grants)Impact (FWCI 4.46)OA: bronzeTopics (37)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Ba Tiep Nguyen ORCID,Phillip Scott ORCID,Fernanda O. Novais ORCID

Live enrichment

PubMed:32738245 PMC:PMC7855313 OpenAlex:https://openalex.org/W3045620684

NIAID NIH HHS

Grant: R01 AI150606

University of Pennsylvania

FWCI

4.46

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.jidonline.org/article/S0022202X20319424/pdf

publisherhttp://www.jidonline.org/article/S0022202X20319424/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0022202X20319424?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022202X20319424?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jid.2020.07.011

Fields of Study

Research on Leishmaniasis StudiesT-cell and Retrovirus StudiesToxin Mechanisms and Immunotoxins

MeSH Terms

AnimalsAntiparasitic AgentsBiopsyDisease Models, AnimalDrug Therapy, CombinationHumansLeishmania braziliensisPiperidinesPyrimidinesSeverity of Illness IndexSkinT-Lymphocytes, CytotoxicLeishmaniasis, CutaneousTh1 CellsAdoptive TransferMiceGranzymesParasite Load

Keywords

TofacitinibGranzyme BImmunologyGranzymeCD8Cutaneous leishmaniasisMedicineCytotoxic T cellImmune systemGranzyme AImmunopathologyT cellBiologyLeishmaniasisPerforinIn vitro

Sustainable Development Goals

SDG 0: Good health and well-being

Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis

FAIR Checklist

Authors (3)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)