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Hypoxia and IL-15 Cooperate to Induce Perforin Expression by CD8 T Cells and Promote Damage to the Skin in Murine Cutaneous Leishmaniasis

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.04.029Source: DataRank Database

Hypoxia and IL-15 Cooperate to Induce Perforin Expression by CD8 T Cells and Promote Damage to the Skin in Murine Cutaneous Leishmaniasis is a research paper published in Journal of Investigative Dermatology (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (8 grants)OA: hybridTopics (49)IDs (PubMed)

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Authors (9)

Laís Amorim Sacramento ORCID,Bridget A. Bowman,Bella Lee ORCID,Chan‐Wang Jerry Lio ORCID,Yao-Da Dong

Live enrichment

PubMed:40373956

NIH

Grant: AI165391

NIH

Grant: R01AI162711

NHMRC

Grant: 1013667

Immune regulation, effector function and therapy

NHMRC

Grant: 1145470

NHMRC

Grant: 1132373

Immunobiology and Immunotherapy of Cancer

Wellcome Trust

Grant: unidentified

unidentified

NIAID NIH HHS

Grant: T32 AI165391

Wellcome Trust

hybridLicense: cc-by

publisherhttps://www.jidonline.org/action/showPdf?pii=S0022202X25004798

publisherhttps://api.elsevier.com/content/article/PII:S0022202X25004798?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022202X25004798?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12802810/

https://doi.org/10.1016/j.jid.2025.04.029

Fields of Study

AnimalsLeishmaniasis, CutaneousMiceInterleukin-15CD8-Positive T-LymphocytesPerforinDisease Models, AnimalMice, Inbred C57BLSkinMacrophagesLeishmania majorFemaleNeutrophilsHypoxiaPore Forming Cytotoxic Proteins

MeSH Terms

Keywords

Interleukin-15Pore Forming Cytotoxic ProteinsPerforinNeutrophilsMacrophagesLeishmaniasis, CutaneousCD8-Positive T-LymphocytesArticleMice, Inbred C57BLMiceDisease Models, AnimalAnimalsFemaleHypoxiaSkinLeishmania majorCD8 T cellsCytotoxicityLeishmania