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1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase

Journal of Lipid Research(2021)10.1016/j.jlr.2021.100154Source: DataRank Database

1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase is a research paper published in Journal of Lipid Research (2021). On theSindex it has a DataRank of 0. It has been cited 20 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access20 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 1.04)OA: goldTopics (43)IDs (PubMed, OpenAlex)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Christian Ruiz ORCID,Emily Montal ORCID,Mónica Garcı́a-Barros,Izolda Mileva,Ashley J. Snider ORCID

Live enrichment

PubMed:34838542 OpenAlex:https://openalex.org/W3216134080

National Cancer Institute

Grant: P01 CA097132

National Institute of General Medical Sciences

Grant: GM130878

National Institutes of Health

Grant: 5R01GM130878-02

Role for Sphingosine Kinase 1 in Serine Deprivation

National Institutes of Health

Grant: 5P01CA097132-02

Sphingolipids in Cancer Therapy and Angiogenesis

FWCI

1.04

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.jlr.2021.100154

publisherhttps://doi.org/10.1016/j.jlr.2021.100154

publisherhttps://api.elsevier.com/content/article/PII:S0022227521001371?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022227521001371?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34838542

Fields of Study

Sphingolipid Metabolism and SignalingEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy0301 basic medicine03 medical and health sciences

MeSH Terms

Sphingosine KinaseAnimalsGlycineHumansNeoplasmsSerineSphingolipidsSphingosinePhosphotransferases (Alcohol Group Acceptor)Cell Line, TumorMiceProteolysis

Keywords

SerineBiochemistryCell biologySphingosineKinaseGlycineBiologySphingolipidChemistryPhosphorylationAmino acidSphingolipidsQD415-436reactive oxygen species (ROS)Phosphotransferases (Alcohol Group Acceptor)Micesphingosine kinaseCell Line, TumorNeoplasmsProteolysisHumansAnimalspyruvate kinase (PKM2)phosphoglycerate dehydrogenase (PHGDH)serine palmitoyl transferase (SPT)Research Article

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good healthSDG 0: Life in Land