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Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen

Journal of Lipid Research(2021)10.1016/j.jlr.2021.100160Source: DataRank Database

Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen is a research paper published in Journal of Lipid Research (2021). On theSindex it has a DataRank of 0. It has been cited 22 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access22 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 2.63)OA: goldTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Ozan Dikilitas ORCID,Michael Mendelson ORCID,Zahra Aligabi ORCID,Promotto Islam,Edward B. Neufeld ORCID

Live enrichment

PubMed:34902367 PMC:PMC8953622 OpenAlex:https://openalex.org/W4220965506

National Institutes of Health

Grant: K99 HL136875

National Heart Lung and Blood Institute

Grant: HL006095

National Institutes of Health

Grant: 1K99HL136875-01

Circulating Epigenetic Biomarkers for Personalized Cardiovascular Disease Prevention

Mayo Clinic

FWCI

2.63

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jlr.2021.100160

publisherhttps://doi.org/10.1016/j.jlr.2021.100160

publisherhttps://api.elsevier.com/content/article/PII:S0022227521001437?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022227521001437?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34902367

Fields of Study

Lipoproteins and Cardiovascular HealthAtherosclerosis and Cardiovascular DiseasesCellular transport and secretion0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

EndocytosisHumansLipoproteins, LDLMicrofilament ProteinsMuscle ProteinsReceptors, LDLSterol Regulatory Element Binding Protein 2Genome-Wide Association StudyHep G2 CellsCRISPR-Cas Systems

Keywords

EndocytosisFamilial hypercholesterolemiaInternalizationLDL receptorEndocytic cycleCRISPRBiologyCell biologyPCSK9Receptor-mediated endocytosisReceptorGeneLipoproteinCholesterolGeneticsBiochemistryLDLHepG2 cellsactin-binding proteinTransgelinCellular Ldl UptakeWhole-genome Crispr-cas9 ScreenMicrofilament ProteinsMuscle ProteinsQD415-436Hep G2 CellsLipoproteins, LDLReceptors, LDLHumansCRISPR-Cas SystemsResearch ArticleSterol Regulatory Element Binding Protein 2Genome-Wide Association Study

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being