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β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.02.021Source: DataRank Database

β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7 is a research paper published in Journal of Molecular Biology (2020). On theSindex it has a DataRank of 0. It has been cited 37 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access37 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 2.74)OA: greenTopics (73)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Devin M. Wolfe,Sandipkumar Darji ORCID,Mary Kate McBrayer,Daniel J. Colacurcio,Asok Kumar

Live enrichment

PubMed:32105735 OpenAlex:https://openalex.org/W3006732691

National Institutes of Health

Grant: 3P01AG017617-07S1

Cell and molecular pathobiology of Alzheimers Disease

NIA NIH HHS

Grant: P01 AG017617

FWCI

2.74

Citation Percentile

0.9%

Citation Trend

2018

2020

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7211125

publisherhttps://api.elsevier.com/content/article/PII:S0022283620301947?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022283620301947?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jmb.2020.02.021

Fields of Study

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolismCellular transport and secretion0301 basic medicine0303 health sciences03 medical and health sciencesAdrenergic beta-2 Receptor AgonistsAlzheimer DiseaseAnimalsCalciumChloride ChannelsChloridesEndoplasmic ReticulumFibroblastsHumansHydrogen-Ion ConcentrationLysosomesMiceMice, KnockoutMutationPresenilin-1Receptors, Adrenergic, beta-2

MeSH Terms

Alzheimer DiseaseAnimalsCalciumChloridesEndoplasmic ReticulumFibroblastsHumansHydrogen-Ion ConcentrationLysosomesMutationChloride ChannelsReceptors, Adrenergic, beta-2Mice, KnockoutMicePresenilin-1Adrenergic beta-2 Receptor Agonists

Keywords

LysosomeAutophagyPSEN1Endoplasmic reticulumCell biologyChemistryHomeostasisEndocytic cyclePresenilinBiologyInternal medicineBiochemistryMedicineReceptorAlzheimer's diseaseEndocytosisMice, KnockoutFibroblastsHydrogen-Ion ConcentrationMiceChloridesAlzheimer DiseaseChloride ChannelsMutationPresenilin-1AnimalsHumansCalciumReceptors, Adrenergic, beta-2LysosomesAdrenergic beta-2 Receptor AgonistsPKARNA-seqacidificationchloride

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being