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Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.10.020Source: DataRank Database

Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains is a research paper published in Journal of Molecular Biology (2020). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Enrichment:Funding (4 grants)OA: greenTopics (43)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Authors (12)

Wazo Myint ORCID,Krista A. Delviks‐Frankenberry ORCID,Shurong Hou ORCID,Tapan Kanai ORCID,Vanivilasini Balachandran

Live enrichment

PubMed:33098858 PMC:PMC7771068

NIGMS NIH HHS

Grant: R01 GM093833

Intramural NIH HHS

Grant: ZIC BC011849

NIAID NIH HHS

Grant: R01 AI150478

National Institutes of Health

Grant: 5R01AI150478-09

Structurally dissecting APOBEC3's for HIV-1 restriction and beyond

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7771068

publisherhttps://api.elsevier.com/content/article/PII:S0022283620305970?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022283620305970?httpAccept=text/plain

https://doi.org/10.1016/j.jmb.2020.10.020

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771068

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

AnimalsMacaca mulattaHumansZincDNA-Binding ProteinsDNA, Single-StrandedCrystallography, X-RayCatalytic DomainProtein ConformationProtein BindingMutationAPOBEC-3G DeaminaseProtein Domains

Keywords

Co-crystal structureCytosine deaminaseApobec3gHiv-1 RestrictionSsdna Binding570Protein ConformationDNA, Single-StrandedAPOBEC-3G DeaminaseCrystallography, X-RayBiochemistryProtein DomainsStructural BiologyVirologyCatalytic DomainEnzymes and CoenzymesAnimalsHumansMolecular BiologyMedicinal-Pharmaceutical ChemistryMacaca mulattaDNA-Binding ProteinsMedicinal Chemistry and PharmaceuticsZincVirusesMutationProtein Binding

Sustainable Development Goals

SDG 3: 3. Good health

Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains

FAIR Checklist

Authors (12)

Funding (4 grants)

Open Access

Topics

Annotations (Europe PMC)