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Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation

Journal of Molecular Biology(2021)10.1016/j.jmb.2020.166795Source: DataRank Database

Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation is a research paper published in Journal of Molecular Biology (2021). On theSindex it has a DataRank of 0. It has been cited 19 times.

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Enrichment:Funding (9 grants)OA: hybridTopics (28)IDs (PubMed)

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Authors (17)

Bailey C. Montefiore ORCID,Mengxi Liu ORCID,D.J. Wood ORCID,Richard A. Heath,James R. Ault ORCID

Live enrichment

PubMed:26207759

Wellcome Trust

Grant: 063551

Medical Research Council

Grant: G0901526

CDK-containing macromolecular assemblies

Medical Research Council

Grant: MR/N009738/1

CDK-containing macromolecular assemblies

National Institutes of Health

Grant: CA76584

National Institutes of Health

Grant: GM136250

Biotechnology and Biological Sciences Research Council

Grant: BB/M012573/1

Probing biomolecular interactions by combining ETD-tandem mass spectrometry with chemical footprinting methodologies.

Cancer Research UK

Grant: C2115/A21421

National Institutes of Health

Grant: 5R37CA076584-10

F-box proteins: deregulated cell cycle control and proteolysis in cancer

National Institutes of Health

Grant: 1R35GM136250-01

Regulation of the cell proliferation by CRL ubiquitin ligases

hybridLicense: cc-by

publisherhttps://www.sciencedirect.com/science/article/pii/S0022283620307208/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0022283620307208?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022283620307208?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7895821

repositoryhttp://hdl.handle.net/10754/667206

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Protein Conformation, alpha-HelicalCyclin ASaccharomyces cerevisiaeubiquitinationcheckpointCyclin ECDC2-CDC28 KinasesHumansProtein Interaction Domains and MotifsS-Phase Kinase-Associated ProteinsBinding SitesCyclin-Dependent Kinase 2protein kinaseG1 Phase Cell Cycle CheckpointsRecombinant ProteinsHEK293 CellsGene Expression RegulationProteolysiscell cycleProtein Conformation, beta-StrandsignalingCyclin-Dependent Kinase Inhibitor p27Research ArticleProtein BindingSignal Transduction