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Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167295Source: DataRank Database

Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States is a research paper published in Journal of Molecular Biology (2021). On theSindex it has a DataRank of 0. It has been cited 49 times.

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Open Access49 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (12 grants)OA: hybridTopics (27)IDs (PubMed, PMC)SDGs (2)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Weikang Ma ORCID,Srinivas Chakravarthy ORCID,Ariana C. Combs ORCID,Na Sa ORCID,Stephen J. Langer ORCID

Live enrichment

PubMed:34627791 PMC:PMC9044501

Argonne National Laboratory

Grant: DE-AC02-06CH11357

Argonne National Laboratory

Grant: P41 GM103622

NIGMS NIH HHS

Grant: P30 GM138395

National Institutes of Health

Grant: 3P41GM103622-19S1

The Biophysics Collaborative Access Team

National Institutes of Health

National Institute of General Medical Sciences

University of California, San Francisco

Office of Science

U.S. Department of Energy

MyoKardia

University of Colorado Boulder

University of Massachusetts

hybridLicense: cc-by

publisherhttps://doi.org/10.1016/j.jmb.2021.167295

publisherhttps://api.elsevier.com/content/article/PII:S0022283621005325?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022283621005325?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9044501

repositoryhttps://www.osti.gov/biblio/1831332

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

BenzylaminesUracilMyosinsVentricular MyosinsSpectrum AnalysisProtein ConformationStructure-Activity RelationshipModels, MolecularProtein Interaction Domains and MotifsProtein Stability

Keywords

BlebbistatinMavacamtenSuper-relaxed State (Srx)Interacting Heads Motif (Ihm)Small Angle-x-ray Scattering (Saxs)Models, MolecularBenzylaminesProtein ConformationProtein StabilitySpectrum AnalysisMyosinsVentricular MyosinsStructure-Activity RelationshipProtein Interaction Domains and MotifsUracil

Sustainable Development Goals

SDG 3: 3. Good healthSDG 12: 12. Responsible consumption