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Development and validation of a paper spray mass spectrometry method for the rapid quantitation of remdesivir and its active metabolite, GS-441524, in human plasma

Journal of Mass Spectrometry and Advances in the Clinical Lab(2022)10.1016/j.jmsacl.2022.06.001Source: DataRank Database

Development and validation of a paper spray mass spectrometry method for the rapid quantitation of remdesivir and its active metabolite, GS-441524, in human plasma is a research paper published in Journal of Mass Spectrometry and Advances in the Clinical Lab (2022). On theSindex it has a DataRank of 0. It has been cited 13 times.

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Scored on demand from live citation data

Open Access13 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.16)OA: goldTopics (66)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Hannah Zimmerman,Nicholas E. Manicke ORCID,Lindsey Kirkpatrick ORCID,Christine Skaggs

Live enrichment

PubMed:35721272 PMC:PMC9188284 OpenAlex:https://openalex.org/W4283215791

National Institutes of Health

Grant: T32HD069047

NIAID NIH HHS

Grant: R25 AI147376

NIAID NIH HHS

Grant: L40 AI147213

FWCI

1.16

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://www.sciencedirect.com/science/article/pii/S2667145X22000165/pdf

GOLDhttps://www.sciencedirect.com/science/article/pii/S2667145X22000165/pdf

publisherhttps://www.sciencedirect.com/science/article/pii/S2667145X22000165/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2667145X22000165?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2667145X22000165?httpAccept=text/plain

Fields of Study

Mass Spectrometry Techniques and ApplicationsPesticide Residue Analysis and SafetyPharmaceutical Quality and CounterfeitingMedicineChemistry

Keywords

Mass spectrometryChromatographyMetabolitePharmacokineticsHuman plasmaActive metaboliteChemistryAntiviral drugCoronavirus disease 2019 (COVID-19)Calibration curveTherapeutic drug monitoringTriple quadrupole mass spectrometerPharmacologyDrugMedicineSelected reaction monitoringTandem mass spectrometryDetection limitBiochemistryAntiviralDmso, Dimethyl SulfoxideLod, Limit Of DetectionAuc, Area Under The CurveIs, Internal StandardCv, Coefficient Of VariationPk, PharmacokineticsPd, PharmacodynamicsQc, Quality ControlLc-ms/ms, Liquid Chromatography–mass SpectrometryPaper SprayLloq, Lower Limit Of QuantitationIrb, Institutional Review BoardΜg, MicrogramMl, MilliliterR2, Coefficient Of DeterminationΜl, MicroliterCe, Collision EnergyNg, NanogramRemdesivirSars-cov-2Anova, A One-way Analysis Of VarianceCes1, Carboxylesterase-1Ces2, Carboxylesterase-2Ec50, Half Maximum Effective ConcentrationH-esi, Heated Electrospray IonizationInc, IncorporatedLlc, Limited Liability CompanyPs-ms/ms, Paper Spray–mass SpectrometryQc-lloq, Quality Control-lower Limit Of QuantificationS/b, Signal-to-blankSil, Stable Isotopically-labeledSs, Spiking SolutionKv, KilovoltsTherapeutic Drug Monitoring, TdmRf, Radio FrequencyM/z, Mass-to-chargeMp, MonophosphateV, VoltsEcmo, Extracorporal Membrane OxygenationµL, microliterµg, microgram

Sustainable Development Goals

SDG 0: Good health and well-being

Development and validation of a paper spray mass spectrometry method for the rapid quantitation of remdesivir and its active metabolite, GS-441524, in human plasma

FAIR Checklist

Authors (4)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)