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LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies

Journal of Pharmaceutical and Biomedical Analysis(2020)10.1016/j.jpba.2020.113093Source: DataRank Database

LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies is a research paper published in Journal of Pharmaceutical and Biomedical Analysis (2020). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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Enrichment:Funding (5 grants)Impact (FWCI 0.00)OA: greenTopics (32)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

King C. Chan ORCID,Jesse M. Jaynes ORCID,Zachary Knotts ORCID,Xia Xu ORCID,Abisola Abisoye-Ogunniyan ORCID

Live enrichment

PubMed:31931447 PMC:PMC8378240 OpenAlex:https://openalex.org/W2996795450

Intramural NIH HHS

Grant: ZIA BC011267

Center for Cancer Research

National Cancer Institute, National Institutes of Health

Intramural Research Program of the NIH

National Cancer Institute

FWCI

0.00

Citation Percentile

0.0%

Citation Trend

2024

2025

greenLicense: https://www.elsevier.com/legal/tdmrep-license

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8378240

publisherhttps://api.elsevier.com/content/article/PII:S0731708519312890?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0731708519312890?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jpba.2020.113093

Fields of Study

Antimicrobial Peptides and ActivitiesImmunotherapy and Immune Responsesvaccines and immunoinformatics approaches

MeSH Terms

AnimalsCarboxylic AcidsChromatography, AffinityChromatography, High Pressure LiquidDrug Evaluation, PreclinicalReproducibility of ResultsAntimicrobial Cationic PeptidesMiceTandem Mass SpectrometryGhrelinLimit of DetectionMagnetic Phenomena

Keywords

ChemistryChromatographyFormic acidSelected reaction monitoringPeptideMass spectrometryTriple quadrupole mass spectrometerDetection limitTandem mass spectrometryLiquid chromatography–mass spectrometryBiochemistryCationic peptidePharmacokinetic StudyLc–ms/msRp-182Solid-phase Magnetic ExtractionSynthetic Host Defense Peptide

Sustainable Development Goals

SDG 0: Good health and well-being

LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies

FAIR Checklist

Authors (15)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)