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Pharmacokinetic analysis of morphine-3-glucuronide after acute morphine intravenous bolus administration to rats with traumatic brain injury

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103645Source: DataRank Database

Pharmacokinetic analysis of morphine-3-glucuronide after acute morphine intravenous bolus administration to rats with traumatic brain injury is a research paper published in Journal of Pharmacology and Experimental Therapeutics (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (5 grants)Impact (FWCI 1.02)OA: hybridTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Jeremy Henchir,Sarah Svirsky,Thomas D. Nolin ORCID,Philip E. Empey ORCID,Shaun W. Carlson ORCID

Live enrichment

PubMed:40729783 PMC:PMC12489372 OpenAlex:https://openalex.org/W4411633538

National Institutes of Health

Grant: S10OD028540

National Institute of Neurological Disorders and Stroke

Grant: R01-NS124730

NINDS NIH HHS

Grant: R01 NS124730

Pittsburgh Foundation

University of Pittsburgh

FWCI

1.02

Citation Percentile

0.8%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://jpet.aspetjournals.org/action/showPdf?pii=S0022356525398587

publisherhttps://jpet.aspetjournals.org/action/showPdf?pii=S0022356525398587

publisherhttps://api.elsevier.com/content/article/PII:S0022356525398587?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022356525398587?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jpet.2025.103645

Fields of Study

Anesthesia and Pain ManagementTraumatic Brain Injury and Neurovascular DisturbancesAnesthesia and Sedative AgentsAnimalsMorphine DerivativesMaleBrain Injuries, TraumaticMorphineRatsRats, Sprague-DawleyAdministration, IntravenousBlood-Brain BarrierBrainInjections, IntravenousAnalgesics, Opioid

MeSH Terms

Brain Injuries, TraumaticAnalgesics, OpioidAnimalsBlood-Brain BarrierBrainInjections, IntravenousMaleMorphineMorphine DerivativesRats, Sprague-DawleyRatsAdministration, Intravenous

Keywords

PharmacokineticsPharmacologyMedicineMorphineNeuroinflammationTraumatic brain injuryPharmacodynamicsMetaboliteMicrodialysisSystemic administrationInflammationBolus (digestion)AnesthesiaCentral nervous systemIn vivoInternal medicineGlial fibrillary acidic proteinM3g

Sustainable Development Goals

SDG 0: Good health and well-being

Pharmacokinetic analysis of morphine-3-glucuronide after acute morphine intravenous bolus administration to rats with traumatic brain injury

FAIR Checklist

Authors (6)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)