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Reprogramming oncogenic mitochondria in pancreatic adenocarcinoma through BRD4 inhibition leads to programmed cell death

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103751Source: DataRank Database

Reprogramming oncogenic mitochondria in pancreatic adenocarcinoma through BRD4 inhibition leads to programmed cell death is a research paper published in Journal of Pharmacology and Experimental Therapeutics (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: greenTopics (29)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Michael W. Spinrad,Lauren C. Gattie ORCID,Rui Wang ORCID,Mohammad Amir Afjal,Jun Yang ORCID

Live enrichment

PubMed:41232326 PMC:PMC13107524 OpenAlex:https://openalex.org/W4415225080

National Institutes of Health

Grant: R01 DK132230

National Institutes of Health

Grant: R01 CA289881

National Institutes of Health National Cancer Institute

Grant: R01 DK117183

National Institutes of Health National Cancer Institute

Grant: R01 CA266600-01A1

NCI NIH HHS

Grant: R01 CA266600

Center for Cancer Research

FWCI

0.00

Citation Percentile

0.3%

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13107524/

publisherhttps://api.elsevier.com/content/article/PII:S002235652540264X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S002235652540264X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jpet.2025.103751

Fields of Study

Pancreatic and Hepatic Oncology ResearchCancer Genomics and DiagnosticsCancer Research and Treatments

MeSH Terms

Bromodomain Containing ProteinsAdenocarcinomaAnimalsAutophagyHumansMitochondriaPancreatic NeoplasmsTranscription FactorsApoptosisCell Cycle ProteinsCarcinoma, Pancreatic DuctalCell Line, TumorMiceMitophagy

Keywords

MitophagyMitochondrionReprogrammingProgrammed cell deathApoptosisCell growthCellIntracellularPancreatic Ductal AdenocarcinomaCancer TherapeuticsMitochondrial StressBromo- And Extraterminal Domain