Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Lysine demethylase 5D promotes CHEK1 inhibitor sensitivity through p38-mediated cyclooxygenase-2 expression in castration-resistant prostate cancer cells

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103769Source: DataRank Database

Lysine demethylase 5D promotes CHEK1 inhibitor sensitivity through p38-mediated cyclooxygenase-2 expression in castration-resistant prostate cancer cells is a research paper published in Journal of Pharmacology and Experimental Therapeutics (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

Download PDF

Cite:

Linked data & code

geo nct doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.74)OA: hybridTopics (38)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (7)

Shichen Li ORCID,Raymond E. West ORCID,Ella R. Donahue,Thomas D. Nolin ORCID,Song Li ORCID

Live enrichment

PubMed:41308413 PMC:PMC12799561 OpenAlex:https://openalex.org/W4415830510

Medical Center, University of Pittsburgh

Grant: P30CA047904

National Institutes of Health National Cancer Institute

Grant: R01CA229431

National Institutes of Health

FWCI

0.74

Citation Percentile

0.7%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://jpet.aspetjournals.org/article/S0022-3565(25)40282-1/pdf

publisherhttps://jpet.aspetjournals.org/article/S0022-3565(25)40282-1/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0022356525402821?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022356525402821?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jpet.2025.103769

Fields of Study

Epigenetics and DNA MethylationProstate Cancer Treatment and ResearchDNA Repair MechanismsHumansMaleCheckpoint Kinase 1Prostatic Neoplasms, Castration-ResistantCyclooxygenase 2Cell Line, Tumorp38 Mitogen-Activated Protein KinasesProtein Kinase InhibitorsHistone DemethylasesDrug Resistance, NeoplasmGene Expression Regulation, Neoplastic

MeSH Terms

Checkpoint Kinase 1HumansMaleGene Expression Regulation, NeoplasticDrug Resistance, NeoplasmCell Line, TumorProtein Kinase Inhibitorsp38 Mitogen-Activated Protein KinasesCyclooxygenase 2Histone DemethylasesProstatic Neoplasms, Castration-Resistant

Keywords

Gene knockdownDemethylaseProstate cancerGene silencingRegulatorDNA damageEpigeneticsCHEK1HistoneProtein kinase inhibitorDrug sensitivityEpigenetic RegulatorCell Cycle Checkpoint Kinase

Lysine demethylase 5D promotes CHEK1 inhibitor sensitivity through p38-mediated cyclooxygenase-2 expression in castration-resistant prostate cancer cells

FAIR Checklist

Authors (7)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)