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OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton

Journal of Structural Biology(2020)10.1016/j.jsb.2020.107627Source: DataRank Database

OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton is a research paper published in Journal of Structural Biology (2020). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.37)OA: greenTopics (85)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Priyam Jani ORCID,Tina M. Kilts,Li Li ORCID,Emily Y. Chu ORCID,Marian F. Young ORCID

Live enrichment

PubMed:32950603 PMC:PMC7744403 OpenAlex:https://openalex.org/W3087064153

Intramural NIH HHS

Grant: Z01 DE000379

National Institutes of Health

Grant: 1Z01DE000379-16

REGULATION AND FUNCTION OF SKELETAL MATRIX GENES

National Institutes of Health

FWCI

0.37

Citation Percentile

0.6%

Citation Trend

2021

2022

2023

2024

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7744403

publisherhttps://api.elsevier.com/content/article/PII:S1047847720302008?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1047847720302008?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jsb.2020.107627

Fields of Study

Bone Metabolism and DiseasesBone health and treatmentsConnective tissue disorders research0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsBiglycanBiomarkersBone and BonesDisease Models, AnimalExtracellular MatrixExtracellular Matrix ProteinsFemaleFibromodulinImmunoglobulin Fc FragmentsMaleMiceMice, Inbred C57BLMice, KnockoutOsteoclastsOsteogenesisOsteoprotegerinPhenotypeRecombinant Fusion ProteinsSkeleton

MeSH Terms

FibromodulinAnimalsBone and BonesDisease Models, AnimalExtracellular MatrixFemaleImmunoglobulin Fc FragmentsMaleMice, Inbred C57BLOsteoclastsOsteogenesisPhenotypeRecombinant Fusion ProteinsSkeletonBiomarkersExtracellular Matrix ProteinsMice, KnockoutMiceOsteoprotegerinBiglycan

Keywords

BiglycanPhenotypeEctopic calcificationOsteoclastSkeleton (computer programming)Extracellular matrixChemistryPathologyBiologyInternal medicineAnatomyCell biologyMedicineCalcificationProteoglycanBiochemistryReceptorOsteoporosisProteoglycansLow Bone MassFibromodulinEctopic OssificationOpg-fcMaleMice, KnockoutExtracellular Matrix ProteinsRecombinant Fusion ProteinsOsteoprotegerinOsteoclastsBone and BonesImmunoglobulin Fc FragmentsMice, Inbred C57BLDisease Models, AnimalMiceOsteogenesisAnimalsFemaleBiomarkersSkeleton

Sustainable Development Goals

SDG 0: Good health and well-being

OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton

FAIR Checklist

Authors (6)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)