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A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats

Kidney International(2021)10.1016/j.kint.2021.03.025Source: DataRank Database

A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats is a research paper published in Kidney International (2021). On theSindex it has a DataRank of 0. It has been cited 42 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access42 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 3.19)OA: bronzeTopics (61)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Xiaolan Chen ORCID,Henry R. Askew Page ORCID,Samuel N. Baldwin ORCID,Maria C. Jordan ORCID,Pyone Myat Thwe ORCID

Live enrichment

PubMed:33836171 PMC:PMC8319106 OpenAlex:https://openalex.org/W3148687971

NIDDK NIH HHS

Grant: P30 DK072517

NIDDK NIH HHS

Grant: R01 DK126070

NEI NIH HHS

Grant: R01 EY013574

British Heart Foundation

Grant: FS/18/41/33762

National Institutes of Health

Grant: 5P30DK072517-02

CORE--CLINICAL RESOURCES

National Institutes of Health

Grant: 5R01DK126070-05

SLC26A3 (DRA) Inhibitors for Treatment of Hyperoxaluria and Nephrolithiasis

NIH

American Heart Association Inc

FWCI

3.19

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.kidney-international.org/article/S0085253821003604/pdf

publisherhttp://www.kidney-international.org/article/S0085253821003604/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0085253821003604?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0085253821003604?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.kint.2021.03.025

Fields of Study

Nitric Oxide and Endothelin EffectsIon Transport and Channel RegulationRenin-Angiotensin System Studies0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsAnoctamin-1Blood PressureChloride ChannelsHypertensionMuscle ContractionMuscle, Smooth, VascularRatsRats, Inbred SHRVasoconstriction

MeSH Terms

Anoctamin-1AnimalsBlood PressureHypertensionMuscle ContractionMuscle, Smooth, VascularRats, Inbred SHRVasoconstrictionChloride ChannelsRats

Keywords

Blood pressureMedicineVascular smooth muscleContraction (grammar)Internal medicineVasoconstrictionSpontaneously hypertensive ratEndocrinologyNifedipineCalciumMesenteric arteriesArterySmooth muscleHypertensionAntihypertensivesVasodilatorsInbred SHRClinical SciencesCardiovascularMuscle, Smooth, VascularChloride ChannelsVascularRats, Inbred SHRAnimalsAnoctamin-1Evaluation of treatments and therapeutic interventionsUrology & NephrologyRats5.1 Pharmaceuticals6.1 PharmaceuticalsMuscleSmoothDevelopment of treatments and therapeutic interventionsBiotechnologyMuscle Contraction

Sustainable Development Goals

SDG 0: Good health and well-being