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XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells

Leukemia Research(2013)10.1016/j.leukres.2013.04.018Source: DataRank Database

XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells is a research paper published in Leukemia Research (2013). On theSindex it has a DataRank of 0.755. It has been cited 13 times, with 9 citing works in its 1-hop citation network.

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0.755DataRank · unranked

Scored on demand from live citation data

13 citations · 9 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.69)OA: greenTopics (52)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 52%Citation Network 48%

Base Score Contribution

0.396

From this paper's citation signal

Citation Network Contribution

0.359

From 8 citing papers with measurable signal

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Authors (7)

Duncan H. Mak,Zhiqiang Wang ORCID,Wencai Ma,Po Yee Mak,Michael Andreeff

Live enrichment

PubMed:23669290 PMC:PMC3700666 OpenAlex:https://openalex.org/W2147907541

National Institutes of Health

Grant: P01 CA055164

National Institutes of Health

Grant: CA016672

NCI NIH HHS

Grant: P30 CA016672

NCI NIH HHS

Grant: P01 CA049639

Paul and Mary Haas Chair in Genetics (M.A)

FWCI

0.69

Citation Percentile

0.7%

Citation Trend

2013

2014

2015

2016

2018

2020

2021

2023

2024

greenLicense: https://www.elsevier.com/tdm/userlicense/1.0/

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/3700666

GREENhttps://europepmc.org/articles/pmc3700666?pdf=render

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/3700666

publisherhttps://api.elsevier.com/content/article/PII:S0145212613001409?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0145212613001409?httpAccept=text/plain

Fields of Study

Ubiquitin and proteasome pathwaysCell death mechanisms and regulationAcute Myeloid Leukemia ResearchMedicineBiology

MeSH Terms

BortezomibNF-KappaB Inhibitor alphaAntineoplastic AgentsBoronic AcidsCell SurvivalHumansLeupeptinsOligopeptidesPyrazinesBlotting, WesternLeukemia, Myeloid, AcuteDown-RegulationGene Expression Regulation, LeukemicOligonucleotides, AntisenseApoptosisHL-60 CellsProto-Oncogene Proteins c-bcl-2Reverse Transcriptase Polymerase Chain ReactionCaspasesI-kappa B ProteinsGene Expression ProfilingCell Line, TumorProteasome Endopeptidase ComplexHSP72 Heat-Shock ProteinsX-Linked Inhibitor of Apoptosis ProteinMyeloid Cell Leukemia Sequence 1 Protein

Keywords

XIAPMG132ProteasomeDownregulation and upregulationProteasome inhibitorMyeloid leukemiaBortezomibCancer researchLactacystinChemistryInhibitor of apoptosisLeukemiaApoptosisCaspase 3CaspaseBiologyGeneImmunologyBiochemistryProgrammed cell deathMultiple myeloma

Sustainable Development Goals

SDG 0: Good health and well-being

XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells

FAIR Checklist

DataRank Breakdown

Authors (7)

Funding (5 grants)

Impact

Open Access

Topics