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Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development

Matrix Biology(2024)10.1016/j.matbio.2024.05.003Source: DataRank Database

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development is a research paper published in Matrix Biology (2024). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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Enrichment:Funding (15 grants)Impact (FWCI 2.75)OA: hybridTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Sumit Bhutada ORCID,Simon J. Foulcer,Niccolò Peruzzi ORCID,Courtney M. Nelson ORCID,Deborah E. Seifert ORCID

Live enrichment

PubMed:38750698 PMC:PMC11526477 OpenAlex:https://openalex.org/W4396856029

Canadian Institutes of Health Research

Grant: 142344

National Institutes of Health

Grant: HL107147

National Institutes of Health

Grant: S10 OD023436

National Institutes of Health

Grant: S10 OD030398

National Institutes of Health

Grant: HL10747

National Institutes of Health

Grant: RO1HL156987

NHLBI NIH HHS

Grant: P01 HL107147

NHLBI NIH HHS

Grant: R01 HL156987

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1S10OD023436-01

High-End Instrumentation (HEI) Grant Program (S10)

National Institutes of Health

Grant: 1S10OD030398-01

Quadrupole Time-of-Flight LC-MS

Hjärt-Lungfonden

American Heart Association Inc

Swedish Heart and Lung Association

Paul Scherrer Institut

FWCI

2.75

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.matbio.2024.05.003

publisherhttps://doi.org/10.1016/j.matbio.2024.05.003

publisherhttps://api.elsevier.com/content/article/PII:S0945053X24000647?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0945053X24000647?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38750698

Fields of Study

Proteoglycans and glycosaminoglycans researchCongenital heart defects researchPeptidase Inhibition and AnalysisAnimalsMiceVersicansADAMTS5 ProteinProteolysisADAMTS1 ProteinGlypicansHeartMice, KnockoutGene Expression Regulation, DevelopmentalHeart Defects, Congenital

MeSH Terms

ADAMTS1 ProteinADAMTS5 ProteinAnimalsHeartHeart Defects, CongenitalMice, KnockoutGene Expression Regulation, DevelopmentalMiceGlypicansVersicansProteolysis

Keywords

VersicanProteolysisADAMTSProteasesCell biologyChemistryBiologyComputational biologyProteoglycanBiochemistryMetalloproteinaseMatrix metalloproteinaseExtracellular matrixEnzymeGlypicanmetalloproteaseDegradomicsTerminomicsMice, KnockoutHeart Defects, CongenitalMiceVersicansGlypicansADAMTS1 ProteinAnimalsGene Expression Regulation, DevelopmentalHeartADAMTS5 ProteinArticle

Sustainable Development Goals

SDG 0: Zero hunger

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development

FAIR Checklist

Authors (10)

Funding (15 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)