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Extracellular matrix stiffness mediates insulin secretion in pancreatic islets via mechanosensitive Piezo1 channel regulated Ca2+ dynamics

Matrix Biology Plus(2024)10.1016/j.mbplus.2024.100148Source: DataRank Database

Extracellular matrix stiffness mediates insulin secretion in pancreatic islets via mechanosensitive Piezo1 channel regulated Ca2+ dynamics is a research paper published in Matrix Biology Plus (2024). On theSindex it has a DataRank of 0. It has been cited 16 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access16 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 3.82)OA: goldTopics (28)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Keifer Holcomb,Amit Sela,Stephanie Morrall,Dae‐Won Park ORCID,Nikki L. Farnsworth ORCID

Live enrichment

PubMed:38803329 OpenAlex:https://openalex.org/W4397023823

Juvenile Diabetes Research Foundation

Grant: 3-APF-2019-749-A-N

Juvenile Diabetes Research Foundation

Grant: 1-FAC-2020-891-A-N

American Diabetes Association

Grant: 7-21-JDF-020

NIDDK

Grant: P30-DK116073

NIDDK

Grant: F31 DK132926

National Institutes of Health

Grant: 5P30DK116073-03

UC Denver Diabetes Research Center

National Institutes of Health

Grant: 1F31DK132926-01A1

The role of the peri-islet extracellular matrix in islet function and the pathogenesis of type 1 diabetes

FWCI

3.82

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.mbplus.2024.100148

publisherhttps://doi.org/10.1016/j.mbplus.2024.100148

publisherhttps://api.elsevier.com/content/article/PII:S2590028524000085?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2590028524000085?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38803329

Fields of Study

Erythrocyte Function and PathophysiologyPancreatic function and diabetesBlood properties and coagulation0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Mechanosensitive channelsExtracellular matrixPancreatic isletsSecretionInternal medicineEndocrinologyCell biologyInsulinExtracellularChemistryIsletBiologyIon channelMedicinePancreatic isletMechanotransductionQH301-705.5Insulin secretionPiezo1Biology (General)Articles from the Special Issue on Intersection of Extracellular Matrix Biology and Biomaterials Design; edited by Ashley Brown and Daniel AlgeStiffness

Sustainable Development Goals

SDG 0: Good health and well-being