Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Identification of State-Specific Proteomic and Transcriptomic Signatures of Microglia-Derived Extracellular Vesicles

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100678Source: DataRank Database

Identification of State-Specific Proteomic and Transcriptomic Signatures of Microglia-Derived Extracellular Vesicles is a research paper published in Molecular & Cellular Proteomics (2023). On theSindex it has a DataRank of 0.677. It has been cited 21 times, with 20 citing works in its 1-hop citation network.

N/A

0.677DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access21 citations · 20 citing works in its network

Download PDF

Cite:

Linked data & code

geo

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE240295

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)OA: goldTopics (23)IDs (PubMed, PMC)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 68%Citation Network 32%

Base Score Contribution

0.464

From this paper's citation signal

Citation Network Contribution

0.213

From 12 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 20 citers.

Microglia-to-neuron signaling links APOE4 and inflammation to enhanced neuronal lipid metabolism and network activity
Proceedings of the National Academy of Sciences202518 citations56 referencesContributes 0.053
Pinctada martensii Hydrolysate Modulates the Brain Neuropeptidome and Proteome in Diabetic (db/db) Mice via the Gut–Brain Axis
Marine Drugs20243 citations47 referencesContributes 0.029
Research progress on the mechanisms of microglial extracellular vesicles affecting the prognosis of ischemic stroke
Neurochemistry International20256 citations66 referencesContributes 0.029
Primary microglia cell cultures in translational research: Strengths and limitations
Journal of Biotechnology202418 citations116 referencesContributes 0.025
Transcriptomic analysis and fusion gene identifications of midbody remnants released from colorectal cancer cells reveals they are molecularly distinct from exosomes and microparticles
PROTEOMICS202411 citations98 referencesContributes 0.025

Authors (9)

Aditya Natu ORCID,Christina C. Ramelow ORCID,Sruti Rayaprolu ORCID,Hailian Xiao ORCID,Vishnu Kumar ORCID

Live enrichment

PubMed:37952696 PMC:PMC10755493

National Institutes of Health

Grant: S10 RR025679

National Institutes of Health

Grant: UL1TR000454

Georgia Clinical and Translational Science Alliance

Grant: UL1TR002378

NINDS NIH HHS

Grant: F31 NS127530

NINDS NIH HHS

Grant: T32 NS096050

NINDS NIH HHS

Grant: R01 NS114130

NIA NIH HHS

Grant: RF1 AG071587

NIA NIH HHS

Grant: R01 AG075820

National Institutes of Health

Grant: 1S10RR025679-01

FEI Transmission Electron Microscope with Tomography Capability

National Institutes of Health

Grant: 5UL1TR002378-09

Georgia Clinical & Translational Science Alliance (Georgia CTSA)

National Institutes of Health

Grant: 1F31NS127530-01

Exosomes: A novel contributor of microglia-mediated neuroinflammation and neurodegeneration.

National Institutes of Health

Grant: 5UL1TR000454-07

Atlanta Clinical and Translational Science Institute (ACTSI) Renewal

National Institutes of Health

Grant: 7RF1AG071587-02

Microglia-specific proteomic mechanisms and biomarkers of neuroinflammation in Alzheimer's disease

National Institutes of Health

Grant: 7R01AG075820-04

Neuron and microglia-specific proteomic signatures of ERK mediated mechanisms of Alzheimer's disease.

National Institutes of Health

Grant: 1R01NS114130-01A1

Targeting Kv1.3 potassium channels for neuro-immunomodulation in Alzheimer's Disease

National Institute on Aging

goldLicense: cc-by

publisherhttp://www.mcponline.org/article/S1535947623001895/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1535947623001895?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1535947623001895?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10755493/pdf/main.pdf

Europe_PMChttps://europepmc.org/articles/PMC10755493

MeSH Terms

MicrogliaHumansLipopolysaccharidesRNA, MessengerGene Expression ProfilingProteomicsExtracellular VesiclesNeuroinflammatory Diseases

Keywords

LPSProteomicsInflammationMicrogliaExosomesExtracellular VesiclesTranscriptomicsRna SequencingLfq-msLipopolysaccharidesResearchGene Expression ProfilingNeuroinflammatory DiseasesHumansRNA, Messenger