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Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination

Med(2021)10.1016/j.medj.2021.03.014Source: DataRank Database

Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination is a research paper published in Med (2021). On theSindex it has a DataRank of 3.0. It has been cited 168 times, with 92 citing works in its 1-hop citation network.

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3.0DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access168 citations · 92 citing works in its network

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Linked data & code

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Data availability

Repositories this paper deposited data in (declared in PubMed).

ClinicalTrials.govNCT02927145

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 25.50)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 26%Citation Network 74%

Base Score Contribution

0.769

From this paper's citation signal

Citation Network Contribution

2.2

From 69 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 92 citers.

The next frontier for malaria vaccination
Nature20235 citations7 referencesContributes 0.256
Recent clinical trials inform the future for malaria vaccines
Communications Medicine202124 citations16 referencesContributes 0.201
Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response
BMC Infectious Diseases202226 citations37 referencesContributes 0.089
Safety and immunogenicity of BK-SE36 in a blinded, randomized, controlled, age de-escalating phase Ib clinical trial in Burkinabe children
Frontiers in Immunology20229 citations27 referencesContributes 0.085
RH5: rationally-designed malaria vaccine antigen improving efficacy
Trends in Parasitology20243 citations18 referencesContributes 0.077

Authors (50)

Sarah E. Silk ORCID,Jordan R. Barrett ORCID,Carolyn M. Nielsen ORCID,Kazutoyo Miura ORCID,Ababacar Diouf ORCID

Live enrichment

PubMed:34223402 PMC:PMC8240500 OpenAlex:https://openalex.org/W3156568793

Wellcome Trust

Grant: 106917/Z/15/Z

Medical Research Council

Grant: MR/K025554/1

MICA: Development and GMP manufacture of a PfRH5 protein vaccine to induce strain-transcending immunity against blood-stage Plasmodium falciparum.

Wellcome Trust

Grant: 089455

Wellcome Trust PhD Programme for Clinicians at the University of Oxford: 'Investigation of the role of Plasmodium falciparum EBA and RH family antigens in immune evasion and as multi-antigen vaccine candidates.'

Wellcome Trust

Grant: 108734/Z/15/Z

National Institute for Health Research (NIHR)

Grant: CL-2019-26-001

Novo Nordisk Fonden

Grant: NNF17OC0026778

National Institute for Health Research (NIHR)

Grant: CL-2012-18-001

Medical Research Council

Grant: MC_UU_00004/05

National Institute for Health Research (NIHR)

Grant: NIHR201409

Wellcome Trust

Grant: 209200/Z/17/Z

National Institute for Health Research (NIHR)

Grant: CL-2016-20-001

Wellcome Trust

Grant: 108734

Towards an Effective Vaccine against Blood-Stage Plasmodium vivax Malaria.

Wellcome Trust

Grant: 209200

The impact of vaccine platform on the cellular drivers of humoral immunity

Wellcome Trust

Grant: 106917

Harnessing Human Antibodies to Deliver Effective Immunoprophylaxis against Difficult Disease Targets.

USAID

NIAID

Medical Research Council

NIHR Oxford Biomedical Research Centre

Wellcome Trust

FWCI

25.50

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttp://www.cell.com/article/S2666634021001161/pdf

publisherhttp://www.cell.com/article/S2666634021001161/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2666634021001161?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2666634021001161?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.medj.2021.03.014

Fields of Study

Malaria Research and ControlBiological Research and Disease Studiesvaccines and immunoinformatics approaches0303 health sciences03 medical and health sciencesAdultHumansMalariaMalaria VaccinesMalaria, FalciparumPlasmodium falciparumVaccinationVaccines, Synthetic

MeSH Terms

AdultHumansMalariaPlasmodium falciparumVaccinationVaccines, SyntheticMalaria, FalciparumMalaria Vaccines

Keywords

MalariaVaccinationImmunologyMalaria vaccineImmune systemVirologyMedicinePlasmodium falciparumVaccineClinical TrialRh5ChmiBlood-stageSystems SerologyAdultVaccines, Synthetic610Clinical AdvancesMalaria VaccinesHumansMalaria, Falciparum

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being