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Structure-destabilizing mutations unleash an intrinsic perforation activity of antiapoptotic Bcl-2 in the mitochondrial membrane enabling apoptotic cell death

Mitochondrial Communications(2023)10.1016/j.mitoco.2023.08.001Source: DataRank Database

Structure-destabilizing mutations unleash an intrinsic perforation activity of antiapoptotic Bcl-2 in the mitochondrial membrane enabling apoptotic cell death is a research paper published in Mitochondrial Communications (2023). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)Impact (FWCI 0.19)OA: goldTopics (32)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Zhi Zhang ORCID,Rui Wang ORCID,Li Huang ORCID,Hao Wu ORCID,Zhenzhen Qiao ORCID

Live enrichment

PubMed:39239250 OpenAlex:https://openalex.org/W4385708631

National Institutes of Health

Grant: R01GM062964

National Natural Science Foundation of China

Grant: 92254301

National Natural Science Foundation of China

Grant: 32230046

Presbyterian Health Foundation

Grant: 20221568

National Institute of General Medical Sciences

Grant: P20GM103640

National Institutes of Health

Grant: 1R01GM062964-01

Functional Structure of Anti-apoptotic Bcl-2 in Membrane

National Institutes of Health

Grant: 1P20GM103640-01

Structural characterization of gamma-glutamyl transferase enzymes

FWCI

0.19

Citation Percentile

0.5%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.mitoco.2023.08.001

publisherhttps://doi.org/10.1016/j.mitoco.2023.08.001

publisherhttps://api.elsevier.com/content/article/PII:S2590279223000044?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2590279223000044?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39239250

Fields of Study

Cell death mechanisms and regulationRNA Interference and Gene DeliveryATP Synthase and ATPases Research0301 basic medicine03 medical and health sciences

Keywords

ApoptosisCell biologyCytochrome cMitochondrionProgrammed cell deathPerforationIntrinsic apoptosisBcl-2-associated X proteinBiologyBcl-2 familyMutantChemistryBacterial outer membraneCellBiochemistryCaspaseCaspase 3Materials scienceGeneCytochrome c releaseQH301-705.5RMedicineBcl-2 protein poreBiology (General)ArticleMitochondrial membrane

Sustainable Development Goals

SDG 0: Good health and well-being