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Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent

Molecular Cell(2020)10.1016/j.molcel.2020.06.008Source: DataRank Database

Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent is a research paper published in Molecular Cell (2020). On theSindex it has a DataRank of 0. It has been cited 61 times.

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Scored on demand from live citation data

Open Access61 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (25 grants)Impact (FWCI 4.04)OA: hybridTopics (72)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Yuwen Chen ORCID,Luke A. Gilbert ORCID,Max A. Horlbeck ORCID,Lenno Krenning ORCID,Grégory Menchon

Live enrichment

PubMed:32619469 PMC:PMC7332992 OpenAlex:https://openalex.org/W3038900729

Dutch Research Council (NWO)

Grant: 711.015.005

Probing the mechanisms of microtubule dynamics using single molecule pharmacology.

NCI NIH HHS

Grant: K99 CA181494

European Research Council

Grant: 609822

Building a Model Cell to Achieve Control of Cellular Organization

NIGMS NIH HHS

Grant: T32 GM007618

NCI NIH HHS

Grant: U01 CA168370

European Research Council

Grant: 677936

Single molecule observation and manipulation of gene expression dynamics to dissect mechanisms of cell cycle entry

NIGMS NIH HHS

Grant: F32 GM116331

NIDA NIH HHS

Grant: R01 DA036858

NIGMS NIH HHS

Grant: P50 GM102706

NCI NIH HHS

Grant: K99 CA204602

Swiss National Science Foundation

Grant: 166608

National Institutes of Health

Grant: 5F32GM116331-03

Systematic Genome-Wide Characterization of Iron Homeostasis

National Institutes of Health

Grant: 1K99CA204602-01

A functional genomics approach to determine the mechanism of cellular response to new anti-cancer drugs

National Institutes of Health

Grant: 5U01CA168370-03

Bay Area Cancer Target Discovery and Development Network

National Institutes of Health

Grant: 1K99CA181494-01A1

Stress response networks in cancer: systematic mapping and therapeutic potential

National Institutes of Health

Grant: 4P50GM102706-05

Center for RNA Systems Biology

National Institutes of Health

Grant: 1P50GM102706-01

PROJECT 1

National Institutes of Health

Grant: 5R01DA036858-03

Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming

KWF Kankerbestrijding

Swiss National Science Foundation

National Institutes of Health

Dutch Research Council (NWO)

Howard Hughes Medical Institute

Stand Up To Cancer

European Research Council

FWCI

4.04

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttp://www.cell.com/article/S1097276520303932/pdf

publisherhttp://www.cell.com/article/S1097276520303932/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276520303932?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276520303932?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2020.06.008

Fields of Study

Microtubule and mitosis dynamicsUbiquitin and proteasome pathwaysCancer Treatment and Pharmacology0301 basic medicine03 medical and health sciences0303 health sciencesAntineoplastic AgentsCell ProliferationCells, CulturedCrystallography, X-RayDrug ContaminationGlycineHumansMicrotubulesMutationNeoplasmsPharmaceutical PreparationsProtein ConformationSulfonesTubulin

MeSH Terms

Antineoplastic AgentsCells, CulturedDrug ContaminationPharmaceutical PreparationsGlycineHumansMicrotubulesMutationNeoplasmsProtein ConformationSulfonesTubulinCrystallography, X-RayCell Proliferation

Keywords

BiologyMicrotubuleCell biologyComputational biologyPharmacologyMicrotubuleschemical geneticsDrug Target IdentificationRigosertibDrug Mechanism Of ActionCrispriCrispraProtein ConformationCellsGlycineAntineoplastic AgentsCrystallography, X-RayArticleSDG 3 - Good Health and Well-beingTubulin/chemistryTubulinNeoplasmsHumansSulfonesCells, CulturedGlycine/analogs & derivativesCell ProliferationCulturedCrystallographyNeoplasms/drug therapySulfones/pharmacologyPharmaceutical PreparationsMutationX-RayMicrotubules/drug effectsPharmaceutical Preparations/chemistryDrug ContaminationAntineoplastic Agents/pharmacology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being