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Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting

Molecular Cell(2020)10.1016/j.molcel.2020.11.026Source: DataRank Database

Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting is a research paper published in Molecular Cell (2020). On theSindex it has a DataRank of 0. It has been cited 36 times.

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Open Access36 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.97)OA: bronzeTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Sarah M. Sulon,Anshul Bhardwaj ORCID,Siri C. van Keulen ORCID,Nguyen Minh Duc ORCID,Daniela K. Laurinavichyute

Live enrichment

PubMed:33321095 PMC:PMC7855534 OpenAlex:https://openalex.org/W3111806298

National Research Foundation of Korea

Grant: NRF-2018R1A2B6001554

National Research Foundation of Korea

Grant: NFR-2019R1A5A2027340

National Heart, Lung, and Blood Institute

Grant: R01HL142310

National Institute of General Medical Sciences

Grant: R01GM104047

National Institute of General Medical Sciences

Grant: R01GM127359

National Institute of General Medical Sciences

Grant: R35GM122541

NCI NIH HHS

Grant: P30 CA056036

National Institute of General Medical Sciences

National Research Foundation of Korea

National Heart, Lung, and Blood Institute

FWCI

0.97

Citation Percentile

0.7%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.cell.com/article/S1097276520308261/pdf

publisherhttp://www.cell.com/article/S1097276520308261/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276520308261?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276520308261?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2020.11.026

Fields of Study

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase SignalingMass Spectrometry Techniques and Applications

MeSH Terms

Protein Conformation, alpha-HelicalProtein Conformation, beta-StrandAmino Acid SequenceAnimalsBinding SitesCalciumCalmodulinCloning, MolecularGenetic VectorsHumansKineticsPhosphorylationProtein BindingRecombinant ProteinsSubstrate SpecificityThermodynamicsGene ExpressionBaculoviridaeSequence AlignmentSequence Homology, Amino AcidCrystallography, X-RaySpodopteraProtein Interaction Domains and MotifsG-Protein-Coupled Receptor Kinase 5Molecular Dynamics SimulationHEK293 CellsSf9 Cells

Keywords

G protein-coupled receptor kinaseBiologyG protein-coupled receptorCalmodulinAllosteric regulationKinaseCell biologyBiochemistryPhosphorylationBiophysicsReceptorSignal transductionEnzymeProtein kinaseCalciumMolecular dynamicsX-ray crystallographyHydrogen/deuterium Exchange Mass Spectrometry

Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting

FAIR Checklist

Authors (11)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)