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Enhancers predominantly regulate gene expression during differentiation via transcription initiation

Molecular Cell(2021)10.1016/j.molcel.2021.01.002Source: DataRank Database

Enhancers predominantly regulate gene expression during differentiation via transcription initiation is a research paper published in Molecular Cell (2021). On theSindex it has a DataRank of 0. It has been cited 51 times.

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Open Access51 citations

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Enrichment:Funding (29 grants)Impact (FWCI 2.59)OA: bronzeTopics (83)IDs (PubMed, PMC, OpenAlex)Annotations (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Ron Schweßinger ORCID,Takayuki Nojima ORCID,Jelena Telenius ORCID,Robert A. Beagrie ORCID,Damien J. Downes ORCID

Live enrichment

PubMed:33539786 PMC:PMC7612206 OpenAlex:https://openalex.org/W3126260145

Wellcome Trust

Grant: 107928

Molecular mechanism and regulatory function of protein coding gene transcriptional termination in mammalian genomes.

Medical Research Council

Grant: G1000801e

Medical Research Council

Grant: MC_UU_00016/1

Medical Research Council

Grant: MC_UU_00016/12

Medical Research Council

Grant: MR/T014067/1

Switching mammalian genes on and off during development, lineage specification, and differentiation, and its impact on human genetic disease

Medical Research Council

Grant: MC_UU_00016/14

Gene regulation by distal regulatory elements in Erythropoiesis and the effect of natural sequence variants.

Medical Research Council

Grant: MC_UU_12009/13

Wellcome Trust

Grant: 106130/Z/14/Z

NIDDK NIH HHS

Grant: R37 DK044746

Wellcome Trust

Grant: 107928/Z/15/Z

Medical Research Council

Grant: 1514228

Medical Research Council

Grant: G1000801b

Wellcome Trust

Grant: 106130

A systematic approach to understanding the biology underpinning GWAS hits.

Wellcome Trust

Grant: 209181

Exploring mechanisms of enhancer action in erythropoiesis

European Research Council

Grant: 339270

Policing mammalian transcriptomes: regulation of long ncRNA synthesis by transcriptional termination, gene loops and R-loops.

Medical Research Council

Grant: G1000801

Medical Research Council

Grant: G1000801j

Medical Research Council

Grant: MC_U137961144

Medical Research Council

Grant: MC_UU_00016/4

Medical Research Council

Grant: MC_UU_12009/4

Wellcome Trust

Grant: 209181/Z/17/Z

Medical Research Council

Grant: MC_PC_15069

Medical Research Council

Grant: MC_UU_12009/15

Medical Research Council

Grant: MC_U137961145

National Institutes of Health

Grant: 5R37DK044746-22

Function of human & mouse Beta-globin locus control regions

Foundation for the National Institutes of Health

Medical Research Council

DBT/Wellcome Trust India Alliance

National Council for Eurasian and East European Research

FWCI

2.59

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1097276521000022/pdf

publisherhttp://www.cell.com/article/S1097276521000022/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276521000022?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276521000022?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2021.01.002

Fields of Study

Genomics and Chromatin DynamicsRNA Research and SplicingRNA and protein synthesis mechanisms0301 basic medicine03 medical and health sciencesAnimalsCell DifferentiationEnhancer Elements, GeneticExonsFetusGene Expression RegulationGene LibraryHSP70 Heat-Shock ProteinsHumansIntronsK562 CellsLiverMiceMice, KnockoutPromoter Regions, GeneticProto-Oncogene Proteins c-mycRNA Polymerase IISignal TransductionTranscription Initiation, Geneticalpha-Globinsbeta-Globins

MeSH Terms

AnimalsCell DifferentiationEnhancer Elements, GeneticExonsFetusGene Expression RegulationHumansIntronsLiverPromoter Regions, GeneticRNA Polymerase IISignal TransductionGene LibraryProto-Oncogene Proteins c-mycMice, KnockoutHSP70 Heat-Shock ProteinsK562 CellsMicealpha-Globinsbeta-GlobinsTranscription Initiation, Genetic

Keywords

BiologyEnhancerRNA polymerase IIEnhancer RNAsTranscription (linguistics)GeneticsGene expressionRegulation of gene expressionGeneTranscription factorPromoterCell biologyTranscriptionGene regulationEnhancersPromoter Proximal PausingPoll Ii RecruitmentMice, KnockoutCell DifferentiationExonsIntronsProto-Oncogene Proteins c-mycMiceEnhancer Elements, GeneticFetusGene Expression RegulationLiveralpha-GlobinsAnimalsHumansHSP70 Heat-Shock ProteinsK562 CellsPromoter Regions, GeneticTranscription Initiation, GeneticGene LibrarySignal Transduction

Enhancers predominantly regulate gene expression during differentiation via transcription initiation

FAIR Checklist

Authors (13)

Funding (29 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)