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mTORC1 promotes cell growth via m6A-dependent mRNA degradation

Molecular Cell(2021)10.1016/j.molcel.2021.03.010Source: DataRank Database

mTORC1 promotes cell growth via m6A-dependent mRNA degradation is a research paper published in Molecular Cell (2021). On theSindex it has a DataRank of 0.714. It has been cited 116 times.

N/A

0.714DataRank · unranked

Scored on demand from live citation data

Open Access116 citations

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Cite:

Linked data & code

geo gen cellosaurus hpa refseq doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (26 grants)Impact (FWCI 8.14)OA: bronzeTopics (97)IDs (PubMed, PMC, OpenAlex)Annotations (6)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.714

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (15)

Gina Lee ORCID,Brian F. Pickering,Cholsoon Jang ORCID,Jin H. Park ORCID,Long He ORCID

Live enrichment

PubMed:33756105 PMC:PMC8356906 OpenAlex:https://openalex.org/W3131172408

NIH

Grant: R01CA186702

NIH

Grant: F32CA221104

NIH

Grant: R01GM051405

NIH

Grant: DP1DK113643

NIH

Grant: R01HL121266

NIH

Grant: 5T32CA203702

NCI NIH HHS

Grant: T32 CA062948

NCI NIH HHS

Grant: P30 CA008748

NINDS NIH HHS

Grant: R35 NS111631

NCI NIH HHS

Grant: T32 CA203702

NCI NIH HHS

Grant: P01 CA120964

NIAMS NIH HHS

Grant: R01 AR057352

NIH HHS

Grant: S10 OD023669

National Institutes of Health

Grant: 1F32CA221104-01

The mRNA methylation program in leukemia

National Institutes of Health

Grant: 5DP1DK113643-02

Metabolism in Action: Quantitative Fluxes in Mammals

National Institutes of Health

Grant: 1T32CA203702-01A1

Molecular and Translational Oncology Research

National Institutes of Health

Grant: 2P30CA008748-43

MOUSE GENETICS

National Institutes of Health

Grant: 2R01GM051405-13

Signal Transduction to p70 S6 Kinase 1

National Institutes of Health

Grant: 5R01CA186702-03

Control of cap-independent translation by N6-methyladenosine and FTO

National Institutes of Health

Grant: 5R01HL121266-03

Molecular and biochemical basis of Lymphangioleiomyomatosis

Howard Hughes Medical Institute

LAM Foundation

American Diabetes Association

Tuberous Sclerosis Alliance

Starr Foundation

Howard Hughes Medical Institute

FWCI

8.14

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1097276521001787/pdf

publisherhttp://www.cell.com/article/S1097276521001787/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276521001787?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276521001787?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2021.03.010

Fields of Study

RNA modifications and cancerHVDC Systems and Fault ProtectionRNA Research and Splicing0301 basic medicine03 medical and health sciencesAdenosineAnimalsBase SequenceCell Cycle ProteinsCell Line, TumorCell ProliferationEukaryotic Initiation FactorsHEK293 CellsHumansMaleMechanistic Target of Rapamycin Complex 1MiceModels, BiologicalProtein BiosynthesisProto-Oncogene Proteins c-mycRNA Splicing FactorsRNA StabilityRNA, MessengerRibosomal Protein S6 KinasesSignal Transduction

MeSH Terms

RNA Splicing FactorsMechanistic Target of Rapamycin Complex 1AdenosineAnimalsBase SequenceHumansMaleModels, BiologicalRNA, MessengerProtein BiosynthesisSignal TransductionProto-Oncogene Proteins c-mycCell Cycle ProteinsRibosomal Protein S6 KinasesRNA StabilityEukaryotic Initiation FactorsCell Line, TumorCell ProliferationMiceHEK293 Cells

Keywords

BiologymTORC1Cell biologyDegradation (telecommunications)Messenger RNAPI3K/AKT/mTOR pathwaySignal transductionGeneticsGenemRNA stabilityProtein translationCmycS6k1Eif4aWtapYthdf ReadersMxd2M(6)a Mrna ModificationMaleBiomedical and clinical sciencesAdenosineRNA StabilityMessengerCell Cycle ProteinsMedical and Health SciencesMiceModels2.1 Biological and endogenous factorsAetiologyEukaryotic Initiation FactorsCancerTumorBiological SciencesRNA Splicing FactorsMechanistic Target of Rapamycin Complex 1Models, BiologicalCell LineProto-Oncogene Proteins c-mycCell Line, TumorAnimalsHumansRNA, MessengerCell ProliferationBase SequenceRibosomal Protein S6 KinasesHealth sciencesBiologicalHEK293 CellsProtein BiosynthesisRNABiochemistry and Cell BiologyDevelopmental Biology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

mTORC1 promotes cell growth via m6A-dependent mRNA degradation

FAIR Checklist

DataRank Breakdown

Authors (15)

Funding (26 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)