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Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Molecular Cell(2021)10.1016/j.molcel.2021.03.032Source: DataRank Database

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance is a research paper published in Molecular Cell (2021). On theSindex it has a DataRank of 0. It has been cited 215 times.

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Open Access215 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)Impact (FWCI 12.07)OA: bronzeTopics (72)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Eva K. Brinkman ORCID,Christ Leemans ORCID,Xabier Vergara ORCID,Robin H. van der Weide ORCID,Ben Morris ORCID

Live enrichment

PubMed:33848455 PMC:PMC8153251 OpenAlex:https://openalex.org/W3155689026

ZonMw

Grant: 91215067

European Research Council

Grant: 694466

Genomics of Chromosome Architecture and Dynamics in Single Cells

NIDDK NIH HHS

Grant: U54 DK107965

National Institutes of Health

Grant: 5U54DK107965-05

Combined Cytological, Genomic, and Functional Mapping of Nuclear Genome Organization

European Commission

Grant: 800924

International Cancer Research Fellowships - 2

ZonMw

European Research Council

NIH

Horizon 2020 Marie Skłodowska-Curie Actions

FWCI

12.07

Citation Percentile

1.0%

Citation Trend

2019

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: CC BY NC ND

journalhttp://www.cell.com/article/S1097276521002276/pdf

publisherhttp://www.cell.com/article/S1097276521002276/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276521002276?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276521002276?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2021.03.032

Fields of Study

DNA Repair MechanismsCRISPR and Genetic EngineeringGenomics and Chromatin Dynamics0301 basic medicine0303 health sciences03 medical and health sciencesBase SequenceCRISPR-Associated Protein 9ChromatinDNA Breaks, Double-StrandedDNA End-Joining RepairDNA RepairEuchromatinGene RearrangementGenome, HumanHeterochromatinHumansINDEL MutationK562 CellsKineticsProtein BindingReproducibility of Results

MeSH Terms

CRISPR-Associated Protein 9Base SequenceChromatinDNA RepairHeterochromatinHumansKineticsProtein BindingReproducibility of ResultsGene RearrangementGenome, HumanK562 CellsEuchromatinDNA Breaks, Double-StrandedINDEL MutationDNA End-Joining Repair

Keywords

BiologyChromatinCell biologyContext (archaeology)DNADNA repairGeneticsCas9Balance (ability)CRISPRGeneNeuroscienceNuclear laminaDouble strand breakHeterochromatinSSTRNhejReporter AssayMmejGene RearrangementDNA End-Joining RepairBase SequenceGenome, HumanCRISPR; Chromatin; DNA repair; MMEJ; NHEJ; SSTR; double strand break; heterochromatin; nuclear lamina; reporter assayReproducibility of ResultsArticleEuchromatinKineticsINDEL MutationCRISPR-Associated Protein 9HumansDNA Breaks, Double-StrandedK562 CellsProtein Binding