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SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage

Molecular Cell(2022)10.1016/j.molcel.2022.01.001Source: DataRank Database

SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage is a research paper published in Molecular Cell (2022). On theSindex it has a DataRank of 0. It has been cited 51 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access51 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 3.62)OA: greenTopics (62)IDs (PubMed, PMC, OpenAlex)Annotations (4)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Rui Miao ORCID,Francisco Navarro ORCID,Zhibin Zhang ORCID,Ying Zhang ORCID,Jun Hu ORCID

Live enrichment

PubMed:35104452 PMC:PMC10392910 OpenAlex:https://openalex.org/W4210681096

National Institutes of Health

Grant: R01DA039566

Consejo Nacional de Ciencia y Tecnología

Grant: 331537

Intramural NIH HHS

Grant: ZIA BC011646

FWCI

3.62

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10392910/pdf/nihms-1781175.pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276522000016?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276522000016?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10392910

Fields of Study

Cancer-related molecular mechanisms researchPARP inhibition in cancer therapyRNA Research and SplicingA549 CellsAnimalsApoptosisCaspase 3Colorectal NeoplasmsDNA Breaks, Double-StrandedDNA Breaks, Single-StrandedDNA RepairGene Expression Regulation, NeoplasticHCT116 CellsHEK293 CellsHep G2 CellsHumansMaleMice, NudeMicroRNAsPoly (ADP-Ribose) Polymerase-1RNA, Long NoncodingSignal TransductionTumor Suppressor Protein p53Mice

MeSH Terms

Poly (ADP-Ribose) Polymerase-1A549 CellsAnimalsDNA RepairHumansMaleMice, NudeColorectal NeoplasmsSignal TransductionGene Expression Regulation, NeoplasticTumor Suppressor Protein p53ApoptosisMicroRNAsHCT116 CellsMiceCaspase 3DNA Breaks, Double-StrandedDNA Breaks, Single-StrandedHep G2 CellsHEK293 CellsRNA, Long Noncoding

Keywords

DNA damageBiologyPoly ADP ribose polymeraseApoptosisDNA repairMolecular biologyDNACell biologyCleavage (geology)Cancer researchGeneticsPolymerasep53Genotoxic StressParp-1LncrnaMir-34

SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage

FAIR Checklist

Authors (13)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)