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The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining

Molecular Cell(2023)10.1016/j.molcel.2023.03.017Source: DataRank Database

The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining is a research paper published in Molecular Cell (2023). On theSindex it has a DataRank of 0. It has been cited 44 times.

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Open Access44 citations

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Enrichment:Funding (9 grants)Impact (FWCI 4.08)OA: bronzeTopics (33)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (18)

Myles K. MacEachern,Clara M. Stiefel,Roopesh Anand ORCID,Colin Sempeck ORCID,Benjamin Nebenfuehr ORCID

Live enrichment

PubMed:37044098 PMC:PMC10164096 OpenAlex:https://openalex.org/W4364361542

NIGMS NIH HHS

Grant: R35 GM137798

NIGMS NIH HHS

Grant: R35 GM143108

NCI NIH HHS

Grant: R01 CA244261

NIGMS NIH HHS

Grant: T32 GM142607

The Francis Crick Institute

Grant: CC2057

NIGMS NIH HHS

Grant: T32 GM008759

NCI NIH HHS

Grant: R01 CA266100

Wellcome Trust

FWCI

4.08

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.cell.com/article/S1097276523002071/pdf

publisherhttp://www.cell.com/article/S1097276523002071/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276523002071?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276523002071?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2023.03.017

Fields of Study

DNA Repair MechanismsCRISPR and Genetic EngineeringPARP inhibition in cancer therapyDNA Breaks, Double-StrandedDNA RepairDNADNA End-Joining RepairHomologous Recombination

MeSH Terms

DNADNA RepairDNA Breaks, Double-StrandedHomologous RecombinationDNA End-Joining Repair

Keywords

BiologyNucleaseDNADNA repairHomologous recombinationGeneticsNon-homologous end joiningTranscription activator-like effector nucleaseCancer researchCell biologyGenome editingGeneGenomeCancerPARPSynthetic LethalityMmejApe2Hr-deficientApex2

Sustainable Development Goals

SDG 0: Good health and well-being

The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining

FAIR Checklist

Authors (18)

Funding (9 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)