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Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1

Molecular Cell(2024)10.1016/j.molcel.2024.06.022Source: DataRank Database

Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1 is a research paper published in Molecular Cell (2024). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Open Access18 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 3.23)OA: bronzeTopics (47)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Holly Kleinschmidt,Jianyu Yang ORCID,Erik M. Leith ORCID,Jenna K. Johnson,Song Tan ORCID

Live enrichment

PubMed:39019045 OpenAlex:https://openalex.org/W4400685234

National Institutes of Health

Grant: R35 GM139654

National Institutes of Health

Grant: R35 GM144135

National Institutes of Health

Grant: R35 GM127034

National Institutes of Health

Grant: T32 GM125592

National Institutes of Health

Grant: 3R35GM139654-05S1

Mechanism of chromatin accessibility, 3D chromosome organization, and their functions in gene regulation

National Institutes of Health

Grant: 5R35GM144135-03

Understanding the predeterminants of transcription factor regulatory activity

National Institutes of Health

Grant: 5T32GM125592-04

Eukaryotic Gene Regulation (EGR) Predoctoral Training Program

National Institutes of Health

Grant: 5R35GM127034-02

Structural studies of chromatin complexes

FWCI

3.23

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

bronzeLicense: CC BY NC ND

journalhttp://www.cell.com/article/S109727652400529X/pdf

publisherhttp://www.cell.com/article/S109727652400529X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S109727652400529X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S109727652400529X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2024.06.022

Fields of Study

FOXO transcription factor regulationRNA modifications and cancerGenomics and Chromatin Dynamics0301 basic medicine03 medical and health sciencesHepatocyte Nuclear Factor 3-alphaHumansTranscription Factor AP-1Protein BindingBinding SitesA549 CellsChromatinChromatin ImmunoprecipitationOligonucleotides

MeSH Terms

A549 CellsBinding SitesChromatinHumansOligonucleotidesProtein BindingTranscription Factor AP-1Chromatin ImmunoprecipitationHepatocyte Nuclear Factor 3-alpha

Keywords

BiologySequence (biology)Binding siteComputational biologyPlasma protein bindingCell biologyMolecular biologyGeneticsHepatocyte Nuclear Factor 3-alphaTranscription Factor AP-1Chromatin ImmunoprecipitationBinding SitesA549 CellsOligonucleotidesHumansArticleChromatinProtein BindingChIP-ISObinding cooperativitybinding specificitypioneer factorsynthetic DNA librarytranscription factor

Sustainable Development Goals

SDG 0: Zero hunger