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Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role

Molecular Cell(2024)10.1016/j.molcel.2024.07.025Source: DataRank Database

Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role is a research paper published in Molecular Cell (2024). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Open Access18 citations

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geo gen hpa

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Enrichment:Funding (4 grants)Impact (FWCI 2.96)OA: greenTopics (70)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Maria Apostolidi ORCID,Khalid A. Garman ORCID,Ahsan Habib Polash ORCID,Mubarak Ishaq Umar ORCID,Qingcai Meng ORCID

Live enrichment

PubMed:39153475 PMC:PMC11455610 OpenAlex:https://openalex.org/W4401637687

Intramural NIH HHS

Grant: Z99 AR999999

NCI NIH HHS

Grant: U54 CA209992

Intramural NIH HHS

Grant: ZIA AR041205

NIGMS NIH HHS

Grant: R01 GM140481

FWCI

2.96

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11455610/pdf/nihms-2017258.pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276524006233?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276524006233?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11455610/

Fields of Study

RNA Research and SplicingRNA modifications and cancerRNA and protein synthesis mechanismsAnimalsFemaleHumansMiceCarrier ProteinsCell Line, TumorCell MovementCell NucleusEpithelial-Mesenchymal TransitionG-QuadruplexesGene Expression Regulation, NeoplasticHEK293 CellsHeterogeneous-Nuclear Ribonucleoprotein Group F-HMembrane ProteinsMice, Inbred NODNeoplasm InvasivenessProtein BindingRNA PrecursorsThyroid Hormone-Binding ProteinsThyroid HormonesTriple Negative Breast NeoplasmsPyruvate Kinase

MeSH Terms

Thyroid Hormone-Binding ProteinsAnimalsCarrier ProteinsCell MovementCell NucleusFemaleHumansMembrane ProteinsMice, NudeNeoplasm InvasivenessProtein BindingPyruvate KinaseRNA PrecursorsThyroid HormonesGene Expression Regulation, NeoplasticMice, Inbred NODHeterogeneous-Nuclear Ribonucleoprotein Group F-HCell Line, TumorMiceG-QuadruplexesHEK293 CellsEpithelial-Mesenchymal TransitionTriple Negative Breast Neoplasms

Keywords

BiologyPKM2Gene expressionMessenger RNARNAGeneNuclear proteinRNA-binding proteinCell biologyRegulation of gene expressionNuclear export signalMolecular biologyGeneticsTranscription factorEnzymeBiochemistryRNA-binding proteinsG-quadruplexG4Par-clipPosttranscriptional Gene RegulationCrosslinking And Immunoprecipitation