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DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

Molecular Cell(2024)10.1016/j.molcel.2024.11.009Source: DataRank Database

DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states is a research paper published in Molecular Cell (2024). On theSindex it has a DataRank of 0. It has been cited 30 times.

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Open Access30 citations

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Enrichment:Funding (9 grants)Impact (FWCI 5.15)OA: hybridTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Joel Hrit ORCID,Alison A. Chomiak ORCID,Stephanie Stransky ORCID,Jordan R. Hoffman ORCID,Rochelle L. Tiedemann ORCID

Live enrichment

PubMed:39631394 PMC:PMC11741932 OpenAlex:https://openalex.org/W4404961983

NCI NIH HHS

Grant: P50 CA254897

NIGMS NIH HHS

Grant: R35 GM152184

NCI NIH HHS

Grant: F32 CA260116

NIGMS NIH HHS

Grant: R35 GM147261

NCI NIH HHS

Grant: R01 CA283463

National Institute of General Medical Sciences

National Institutes of Health

American Cancer Society

National Cancer Institute

FWCI

5.15

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.molcel.2024.11.009

publisherhttps://doi.org/10.1016/j.molcel.2024.11.009

publisherhttps://api.elsevier.com/content/article/PII:S1097276524009146?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276524009146?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39631394

Fields of Study

Epigenetics and DNA MethylationGenomics and Chromatin DynamicsRNA modifications and cancer

MeSH Terms

DNA (Cytosine-5-)-Methyltransferase 1Colonic NeoplasmsDNA (Cytosine-5-)-MethyltransferasesHeterochromatinHistonesHumansLysineMethyltransferasesPromoter Regions, GeneticHistone-Lysine N-MethyltransferaseRepressor ProteinsSignal TransductionGene Expression Regulation, NeoplasticCpG IslandsDNA MethylationCCAAT-Enhancer-Binding ProteinsUbiquitin-Protein LigasesHCT116 CellsCell Line, TumorCell ProliferationUbiquitinationHEK293 Cells

Keywords

BiologyHeterochromatinHeterochromatin protein 1CrosstalkDNA methylationGeneticsDNAEpigeneticsCell biologyChromatinGenePhysicsGene expressionOpticshistone methylationEpigenetic TherapyUhrf1Histone UbiquitinationSuv39h1/h2

Sustainable Development Goals

SDG 0: Zero hunger

DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

FAIR Checklist

Authors (13)

Funding (9 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)