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TREM2 alters the phagocytic, apoptotic and inflammatory response to Aβ42 in HMC3 cells

Molecular Immunology(2021)10.1016/j.molimm.2020.12.035Source: DataRank Database

TREM2 alters the phagocytic, apoptotic and inflammatory response to Aβ42 in HMC3 cells is a research paper published in Molecular Immunology (2021). On theSindex it has a DataRank of 0. It has been cited 68 times.

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Scored on demand from live citation data

Open Access68 citations

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doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 3.76)OA: greenTopics (65)Linked Datasets (12)DataCite Reuse (12)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (5)

Yvonne Shao,Shane Formica ORCID,Maria Khrestian ORCID,Lynn M. Bekris ORCID,Rumana Akhter ORCID

Live enrichment

PubMed:33461764 PMC:PMC8147571 OpenAlex:https://openalex.org/W3118400946

National Institutes of Health

Grant: R56 AG063870

National Institutes of Health

Grant: R00AG034214

National Institutes of Health

Grant: 1R56AG063870-01

Peripheral TREM2 Epigenetics and the Immune Response in Neurodegenerative Disorders

National Institutes of Health

Grant: 4R00AG034214-03

Biomarker Expression and Regulatory Haplotypes in Alzheimer's Disease

FWCI

3.76

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8147571

publisherhttps://api.elsevier.com/content/article/PII:S0161589020306027?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0161589020306027?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molimm.2020.12.035

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysNeurological Disease Mechanisms and Treatments0301 basic medicine0303 health sciences03 medical and health sciencesAlzheimer DiseaseAmyloid beta-PeptidesApoptosisBrainCell LineCell Line, TumorHep G2 CellsHumansInflammationMembrane GlycoproteinsMicrogliaPhagocytesPhagocytosisPlaque, AmyloidReceptors, ImmunologicTHP-1 CellsU937 Cells

MeSH Terms

THP-1 CellsAlzheimer DiseaseBrainCell LineHumansInflammationMembrane GlycoproteinsPhagocytesPhagocytosisReceptors, ImmunologicAmyloid beta-PeptidesApoptosisMicrogliaU937 CellsCell Line, TumorHep G2 CellsPlaque, Amyloid

Keywords

MicrogliaTREM2PhagocytosisApoptosisCell biologyInflammationBiologyImmune systemImmunologyBiochemistryAβInflammatory FactorsPhagocytesAmyloid beta-PeptidesMembrane GlycoproteinsTHP-1 CellsBrainPlaque, AmyloidHep G2 CellsU937 CellsCell LineAlzheimer DiseaseCell Line, TumorHumansReceptors, Immunologic

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

10.6084/m9.figshare.24940635.v1figshare

Additional file 1 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

10.6084/m9.figshare.24940635figshare

Additional file 1 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675186.v1figshare

Additional file 1 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675186figshare

Additional file 2 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675189.v1figshare

Additional file 2 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675189figshare

Additional file 3 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675192.v1figshare

Additional file 3 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675192figshare

Additional file 4 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675195.v1figshare

Additional file 4 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease

10.6084/m9.figshare.26675195figshare

Additional file 2 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

10.6084/m9.figshare.24940872.v1figshare

Additional file 2 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

10.6084/m9.figshare.24940872figshare