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Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model

Molecular Metabolism(2023)10.1016/j.molmet.2023.101680Source: DataRank Database

Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model is a research paper published in Molecular Metabolism (2023). On theSindex it has a DataRank of 0.601. It has been cited 17 times, with 11 citing works in its 1-hop citation network.

N/A

0.601DataRank · unranked

Scored on demand from live citation data

Open Access17 citations · 11 citing works in its network

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Linked data & code

doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 2.49)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 72%Citation Network 28%

Base Score Contribution

0.434

From this paper's citation signal

Citation Network Contribution

0.168

From 11 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 11 citers.

Endotrophin as a risk marker of mortality and kidney complications in a type 1 diabetes cohort
Frontiers in Molecular Biosciences20234 citations37 referencesContributes 0.043
The fibroblast hormone Endotrophin is a biomarker of mortality in chronic diseases
Matrix Biology202420 citations74 referencesContributes 0.041
Combination Therapy of RAS Inhibition and SGLT2 Inhibitors Decreases Levels of Endotrophin in Persons with Type 2 Diabetes
Biomedicines20237 citations53 referencesContributes 0.039
Modulation of podocyte extracellular matrix remodeling in membranous nephropathy by the NFATc3/LRRC55/BK channel pathway
Journal of Cell Communication and Signaling20251 citations55 referencesContributes 0.013
Targeting COL6A3-C5 with nigericin suppresses endotrophin formation and enhances insulin sensitivity in obesity
Experimental & Molecular Medicine20261 citations61 referencesContributes 0.011

Authors (10)

Wei Xiong ORCID,Shiuhwei Chen,Dawei Bu,Joseph M. Rutkowski ORCID,Joel P. Berger

Live enrichment

PubMed:36696925 PMC:PMC9918787 OpenAlex:https://openalex.org/W4317708430

NIDDK NIH HHS

Grant: P30 DK056338

NIDDK NIH HHS

Grant: R01 DK055758

NIDDK NIH HHS

Grant: R01 DK127274

NIDDK NIH HHS

Grant: R03 DK135783

NIDDK NIH HHS

Grant: K01 DK125447

NIDDK NIH HHS

Grant: P30 DK127984

NIDDK NIH HHS

Grant: RC2 DK118620

NIDDK NIH HHS

Grant: R01 DK099110

NIDDK NIH HHS

Grant: R01 DK131537

National Institutes of Health

Grant: 5R01DK099110-08

White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin

National Institutes of Health

Grant: 5R01DK131537-03

Physiological Role of Dedifferentiating Dermal Adipose Tissue

National Institutes of Health

Grant: 5RC2DK118620-05

Generation of Novel Genetic Tools to Study Cellular Heterogeneity in Adipose Tissues

National Institutes of Health

Grant: 5R01DK127274-02

Metabolic Benefits of Leptin Reduction

National Institutes of Health

Grant: 5P30DK056338-18

Texas Medical Center Digestive Diseases Center

National Institutes of Health

Grant: 1R01DK055758-01A1

ACRP, A PROTEIN SECRETED FROM ADIPOSE TISSUE

National Institutes of Health

Grant: 5K01DK125447-03

Adipocyte mitochondrial distress drives the intercommunication between white and brown adipose tissues

FWCI

2.49

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.molmet.2023.101680

publisherhttps://doi.org/10.1016/j.molmet.2023.101680

publisherhttps://api.elsevier.com/content/article/PII:S2212877823000145?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2212877823000145?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36696925

Fields of Study

Renal Diseases and GlomerulopathiesChronic Kidney Disease and DiabetesAcute Kidney Injury Research0301 basic medicine0303 health sciences03 medical and health sciencesMiceAnimalsPodocytesPeptide FragmentsFibrosisRenal Insufficiency, ChronicAntibodiesCollagen Type VI

MeSH Terms

AnimalsAntibodiesFibrosisPeptide FragmentsCollagen Type VIPodocytesMiceRenal Insufficiency, Chronic

Keywords

PodocyteFibrosisMedicineKidney diseaseRenal functionKidneyAntibodyProteinuriaInflammationImmunologyPathologyInternal medicineRenal fibrosisChronic Kidney DiseasePodocytesPodocinEndotrophinAntibody TreatmentCollagen Type VIBrief CommunicationRC31-1245Peptide FragmentsAntibodiesMiceAnimalsRenal Insufficiency, Chronic

Sustainable Development Goals

SDG 0: Good health and well-being

Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (10)

Funding (16 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)