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Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation

Molecular Metabolism(2023)10.1016/j.molmet.2023.101804Source: DataRank Database

Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation is a research paper published in Molecular Metabolism (2023). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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Enrichment:Funding (13 grants)Impact (FWCI 1.10)OA: goldTopics (77)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Eleonora Scorletti ORCID,Joseph L. Dempsey ORCID,Delfin Buyco ORCID,Chelsea Lin ORCID,Yedidya Saiman ORCID

Live enrichment

PubMed:37714377 PMC:PMC10561121 OpenAlex:https://openalex.org/W4386701458

National Institutes of Health

Grant: 2R01AA026302-07

Molecular mechanisms of post-transplant recurrent alcoholic liver disease

National Institutes of Health

Grant: T32-DK007742

Merck

Grant: NIH-P30-DK050306

Medical University of South Carolina

Grant: P30 CA138313

Medical University of South Carolina

Grant: P30 GM103339

NIAAA NIH HHS

Grant: R01 AA026302

NIDDK NIH HHS

Grant: T32 DK007742

NIDDK NIH HHS

Grant: P30 DK050306

National Institutes of Health

Grant: 5T32DK007742-17

University of Washington GI Training Grant

National Institutes of Health

Grant: 5P30DK050306-08

Center for Digestive and Liver Diseases

National Institutes of Health

Grant: 5P30CA138313-09

Medical University of South Carolina - Cancer Center Support Grant

National Institutes of Health

Grant: 5P30GM103339-02

LIPIDOMISC PORTAL AND SUSTANIABILITY PLAN

Intercept Pharmaceuticals

FWCI

1.10

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.molmet.2023.101804

publisherhttps://doi.org/10.1016/j.molmet.2023.101804

publisherhttps://api.elsevier.com/content/article/PII:S2212877823001382?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2212877823001382?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37714377

Fields of Study

Sphingolipid Metabolism and SignalingAlcohol Consumption and Health EffectsLiver Disease Diagnosis and TreatmentAnimalsFemaleHumansMaleMiceCeramidesEthanolFatty LiverGlucoseHomeostasisInsulinsLipid DropletsLiver Diseases, AlcoholicMice, Inbred C57BLPerilipin-2Sphingosine N-AcyltransferaseOxidoreductasesMembrane Proteins

MeSH Terms

Perilipin-2EthanolAnimalsCeramidesFatty LiverFemaleGlucoseHomeostasisHumansLiver Diseases, AlcoholicMaleMembrane ProteinsMice, Inbred C57BLOxidoreductasesSphingosine N-AcyltransferaseMiceInsulinsLipid Droplets

Keywords

CeramideHomeostasisDownregulation and upregulationEnergy homeostasisLipid metabolismChemistryEndocrinologyEnergy metabolismInternal medicineCell biologyMedicineBiochemistryBiologyApoptosisObesityInsulin resistanceCers6Perilipin2Alcohol-associated Liver DiseaseMaleInsulinsCeramidesPerilipin-2MiceSphingosine N-AcyltransferaseAnimalsHumansLiver Diseases, AlcoholicEthanolMembrane ProteinsLipid DropletsRC31-1245Fatty LiverMice, Inbred C57BLGlucoseOriginal ArticleFemaleOxidoreductases

Sustainable Development Goals

SDG 0: Good health and well-being

Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation

FAIR Checklist

Authors (15)

Funding (13 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)