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Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077

Molecular Pharmacology(2025)10.1016/j.molpha.2025.100076Source: DataRank Database

Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077 is a research paper published in Molecular Pharmacology (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (8 grants)Impact (FWCI 0.00)OA: bronzeTopics (41)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

E. Kyriakis ORCID,Julia Schauer,Magnus Chan,Ying Dou ORCID,Jodene Eldstrom ORCID

Live enrichment

PubMed:41175503 PMC:PMC12799529 OpenAlex:https://openalex.org/W4415799958

Heart and Stroke Foundation of Canada

Grant: G-24-0036478

Heart and Stroke Foundation of Canada

Grant: G-21-0031566

Canadian Institutes of Health Research

Grant: PJT-518041

Canadian Institutes of Health Research

Grant: PJT-156181

Michael Smith Health Research BC

Grant: RT-2022-2735

Natural Sciences and Engineering Research Council of Canada

Grant: RGPIN-2022-03021

Intramural NIH HHS

Grant: Z01 CL002077

Natural Sciences and Engineering Research Council of Canada

Grant: unidentified

unidentified

FWCI

0.00

Citation Percentile

0.4%

bronzeLicense: CC BY NC ND

journalhttps://molpharm.aspetjournals.org/article/S0026-895X(25)15636-8/pdf

publisherhttps://molpharm.aspetjournals.org/article/S0026-895X(25)15636-8/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0026895X25156368?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0026895X25156368?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molpha.2025.100076

Fields of Study

Cardiac electrophysiology and arrhythmiasIon channel regulation and functionCardiac Arrhythmias and Treatments0303 health sciences03 medical and health sciences

MeSH Terms

Action PotentialsAnimalsHumansPyridinesPatch-Clamp TechniquesPotassium Channels, Voltage-GatedPotassium Channel BlockersMyocytes, CardiacKCNQ1 Potassium ChannelHEK293 Cells

Keywords

RepolarizationElectrophysiologyContext (archaeology)Long QT syndromehERGPotassium channelCardiac action potentialCardiac electrophysiologyProtein subunitCardiac RepolarizationCardiac PhysiologyShort Qt SyndromeIon Channel PharmacologyKv7.1 (Kcnq1)Ucl2077HEK293 CellsPatch-Clamp TechniquesPyridinesPotassium Channels, Voltage-GatedKCNQ1 Potassium ChannelPotassium Channel BlockersHumansAnimalsAction PotentialsMyocytes, CardiacArticle

Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077

FAIR Checklist

Authors (7)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)