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Synthesis and biological evaluation of 20(S)-substituted FL118 conjugates as novel antitumor agents

Journal of Molecular Structure(2022)10.1016/j.molstruc.2022.133661Source: DataRank Database

Synthesis and biological evaluation of 20(S)-substituted FL118 conjugates as novel antitumor agents is a research paper published in Journal of Molecular Structure (2022). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.00)OA: greenTopics (16)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Mengke Wang ORCID,Weitong Hu,Hanlin Yue,Endian Yu,Xiangli Zhang ORCID

Live enrichment

PubMed:39545022 PMC:PMC11563187 OpenAlex:https://openalex.org/W4284687482

National Cancer Institute

Grant: CA176937

National Natural Science Foundation of China

Grant: 31270397

NCI NIH HHS

Grant: R44 CA176937

NCI NIH HHS

Grant: R43 CA275410

National Institutes of Health

FWCI

0.00

Citation Percentile

0.0%

greenLicense: https://doi.org/10.15223/policy-004

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11563187

publisherhttps://api.elsevier.com/content/article/PII:S0022286022013175?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022286022013175?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molstruc.2022.133661

Fields of Study

Cancer therapeutics and mechanismsPhotodynamic Therapy Research StudiesSynthesis and biological activity

Keywords

ChemistryConjugateCombinatorial chemistryCancer researchBiochemistryStereochemistryCancerAntitumor activityFl118Camptothecin (Cpt)Lactone StabilityFl118 AnalogTopoisomerase I (Topo1)