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TNF and IL6/Jak2 signaling pathways are the main contributors of the glia-derived neuroinflammation present in Lafora disease, a fatal form of progressive myoclonus epilepsy

Neurobiology of Disease(2022)10.1016/j.nbd.2022.105964Source: DataRank Database

TNF and IL6/Jak2 signaling pathways are the main contributors of the glia-derived neuroinflammation present in Lafora disease, a fatal form of progressive myoclonus epilepsy is a research paper published in Neurobiology of Disease (2022). On theSindex it has a DataRank of 0. It has been cited 27 times.

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Open Access27 citations

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Enrichment:Funding (5 grants)Impact (FWCI 3.37)OA: goldTopics (52)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Rosa Viana ORCID,Mireia Moreno‐Estellés ORCID,Ángela Campos‐Rodríguez,Pascual Sanz ORCID,Teresa Rubio ORCID

Live enrichment

PubMed:36526090 PMC:PMC10682476 OpenAlex:https://openalex.org/W4313422396

NINDS NIH HHS

Grant: P01 NS097197

National Institutes of Health

Grant: 5P01NS097197-04

Lafora Epilepsy - Basic mechanisms to therapy

Fundació la Marató de TV3

Spain Ministry of Science and Innovation

National Institutes of Health

FWCI

3.37

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://www.sciencedirect.com/science/article/pii/S0969996122003564/pdf

publisherhttps://www.sciencedirect.com/science/article/pii/S0969996122003564/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0969996122003564?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969996122003564?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.nbd.2022.105964

Fields of Study

Glycogen Storage Diseases and MyoclonusGenetics and Neurodevelopmental DisordersAutoimmune Neurological Disorders and Treatments0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Neuroinflammatory DiseasesAnimalsNeurogliaSignal TransductionInterleukin-6Myoclonic Epilepsies, ProgressiveLafora DiseaseTumor Necrosis FactorsMiceJanus Kinase 2Protein Tyrosine Phosphatases, Non-Receptor

Keywords

NeuroinflammationLafora diseaseProgressive myoclonus epilepsyEpilepsyInflammasomeMyoclonusMicrogliaDownregulation and upregulationMedicineAstrogliosisImmunologyInflammationBiologyNeurosciencePathologyCentral nervous systemCell biologyGeneticsGeneTNFAstrocytesIL6Lymphocyte InfiltrationInterleukin-6Neurosciences. Biological psychiatry. NeuropsychiatryJanus Kinase 2Myoclonic Epilepsies, ProgressiveProtein Tyrosine Phosphatases, Non-ReceptorMiceNeuroinflammatory DiseasesTumor Necrosis FactorsAnimalsNeurogliaRC321-571Signal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

TNF and IL6/Jak2 signaling pathways are the main contributors of the glia-derived neuroinflammation present in Lafora disease, a fatal form of progressive myoclonus epilepsy

FAIR Checklist

Authors (5)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)