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Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization

Neurobiology of Disease(2023)10.1016/j.nbd.2023.106192Source: DataRank Database

Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization is a research paper published in Neurobiology of Disease (2023). On theSindex it has a DataRank of 0. It has been cited 29 times.

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Open Access29 citations

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Enrichment:Funding (6 grants)Impact (FWCI 2.85)OA: goldTopics (53)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Yong Ren ORCID,Zhen Yan ORCID,Prachetas J. Patel

Live enrichment

PubMed:37302762 PMC:PMC10519202 OpenAlex:https://openalex.org/W4380261276

National Institutes of Health

Grant: AG064656

National Institutes of Health

Grant: AG079797

NIA NIH HHS

Grant: R01 AG064656

NIA NIH HHS

Grant: R01 AG079797

National Institutes of Health

Grant: 5R01AG079797-03

Transcriptomic and Circuitry Aberrations in Alzheimer’s Disease

National Institutes of Health

Grant: 5R01AG064656-05

Targeting Histone K4 Methylation for Treatment of Alzheimer's Disease and Related Dementia

FWCI

2.85

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.nbd.2023.106192

publisherhttps://doi.org/10.1016/j.nbd.2023.106192

publisherhttps://api.elsevier.com/content/article/PII:S0969996123002073?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969996123002073?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37302762

Fields of Study

Genomics and Chromatin DynamicsEpigenetics and DNA MethylationRNA Research and Splicing03 medical and health sciences0302 clinical medicineFemaleHumansCCCTC-Binding FactorAlzheimer DiseaseEpigenesis, GeneticEpigenomicsChromatinBinding SitesBrain

MeSH Terms

CCCTC-Binding FactorAlzheimer DiseaseBinding SitesBrainChromatinFemaleHumansEpigenesis, GeneticEpigenomics

Keywords

CTCFBiologyEpigeneticsChromatinEpigenomicsGeneticsChromatin immunoprecipitationGeneHistoneMECP2Transcription factorCell biologyGene expressionDNA methylationPhenotypePromoterEnhancerAlzheimer's diseaseHistone acetylationChromatin organizationSynaptic GenesCCCTC-Binding FactorBinding SitesBrainNeurosciences. Biological psychiatry. NeuropsychiatryEpigenesis, GeneticAlzheimer DiseaseHumansFemaleRC321-571

Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization

FAIR Checklist

Authors (3)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)