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APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses

Neurobiology of Disease(2025)10.1016/j.nbd.2025.106983Source: DataRank Database

APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses is a research paper published in Neurobiology of Disease (2025). On theSindex it has a DataRank of 0. It has been cited 23 times.

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Open Access23 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (11 grants)OA: goldTopics (22)IDs (PubMed, PMC)

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Authors (10)

Isaiah O. Stephens ORCID,Cathryn T Smith ORCID,Sangderk Lee ORCID,Diksha Satish,Nicholas A. Devanney ORCID

Live enrichment

PubMed:40451545 PMC:PMC12187248

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK133184

National Institute on Aging

Grant: RF1NS118558

National Institute on Aging

Grant: R01AG070830

National Institute on Aging

Grant: R01AG080589

National Institute on Aging

Grant: R01AG081421-S1

National Institute on Aging

Grant: R01AG062550

NIA NIH HHS

Grant: R01 AG081421

NIGMS NIH HHS

Grant: P20 GM148326

California Missions Foundation

National Institutes of Health

Alzheimer's Association

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.nbd.2025.106983

publisherhttps://api.elsevier.com/content/article/PII:S0969996125001998?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969996125001998?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12187248

repositoryhttps://doaj.org/article/547f26b4fcec4fc8883617a876182b12

MeSH Terms

MicrogliaAnimalsMice, Inbred C57BLMice, TransgenicHumansMiceAlzheimer DiseaseInflammationLipopolysaccharidesProteomeMaleApolipoprotein E4Lipid Droplets

Keywords

Alzheimer's diseaseProteomicsApolipoprotein E4Microglialipid dropletsFatty acid metabolismneuroinflammationApoe4Lipidomic