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The complex phenotype and function of spinal cord microglia during ALS progression and the impact of metabotropic glutamate receptor type 5 down-regulation in SOD1G93A mice

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107017Source: DataRank Database

The complex phenotype and function of spinal cord microglia during ALS progression and the impact of metabotropic glutamate receptor type 5 down-regulation in SOD1G93A mice is a research paper published in Neurobiology of Disease (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (1 grants)OA: goldTopics (37)IDs (PubMed)

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Authors (19)

Carola Torazza ORCID,Tiziana Altosole,Silvia Ravera ORCID,Emanuele Farinini,Sara Tessitore

Live enrichment

PubMed:40618857

Ministero dell'Istruzione dell'Università e della Ricerca

Grant: RBSI14B1Z1

Neuronal and non-neuronal depletion of Group I metabotropic glutamate receptors in ALS: an innovative way to hit upon a therapy

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.nbd.2025.107017

publisherhttps://api.elsevier.com/content/article/PII:S0969996125002335?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969996125002335?httpAccept=text/plain

repositoryhttps://doaj.org/article/80ef77da4a2f4fd9b87cceded3bdcb84

repositoryhttps://hdl.handle.net/11567/1258608

Fields of Study

03 medical and health sciences0302 clinical medicine

MeSH Terms

Spinal CordMicrogliaAnimalsMice, Inbred C57BLMice, TransgenicMiceAmyotrophic Lateral SclerosisDisease Models, AnimalDisease ProgressionDown-RegulationPhenotypeReceptor, Metabotropic Glutamate 5Superoxide Dismutase-1

Keywords

AstrocytesMicrogliaAmyotrophic Lateral SclerosisMetabotropic Glutamate Receptor 5Negative Allosteric ModulatorCtepSod1(g93a)Receptor, Metabotropic Glutamate 5Down-RegulationNeurosciences. Biological psychiatry. NeuropsychiatryMice, TransgenicAmyotrophic lateral sclerosis; Astrocytes; CTEP; Metabotropic glutamate receptor 5; Microglia; Negative allosteric modulator; SOD1(G93A)SOD1G93AMice, Inbred C57BLMiceDisease Models, AnimalSuperoxide Dismutase-1PhenotypeSpinal CordDisease ProgressionAnimalsRC321-571

The complex phenotype and function of spinal cord microglia during ALS progression and the impact of metabotropic glutamate receptor type 5 down-regulation in SOD1G93A mice

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Authors (19)

Funding (1 grants)

Open Access

Topics