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Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107048Source: DataRank Database

Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis is a research paper published in Neurobiology of Disease (2025). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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Enrichment:Funding (8 grants)Impact (FWCI 5.09)OA: goldTopics (52)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Himanish Basu ORCID,Yong Lu ORCID,Matthew Bergstresser ORCID,Liwei Sun ORCID,Dylan V. Neel ORCID

Live enrichment

PubMed:40759286 PMC:PMC12412056 OpenAlex:https://openalex.org/W4412980668

National Institute on Aging

Grant: T32 AG000222

National Institute on Aging

Grant: 5F32AG084174-02

NIA NIH HHS

Grant: F32 AG084174

NIDDK NIH HHS

Grant: R01 DK127257

National Institutes of Health

The Chan Zuckerberg Initiative

Fidelity Biosciences

Target ALS

FWCI

5.09

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by-nc

journalhttps://doi.org/10.1016/j.nbd.2025.107048

publisherhttps://doi.org/10.1016/j.nbd.2025.107048

publisherhttps://api.elsevier.com/content/article/PII:S0969996125002645?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969996125002645?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40759286

Fields of Study

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders ResearchNeurological diseases and metabolismAnimalsPyroptosisAmyotrophic Lateral SclerosisMicePhosphate-Binding ProteinsMice, Inbred C57BLDisease Models, AnimalMaleMice, TransgenicSuperoxide Dismutase-1Intracellular Signaling Peptides and ProteinsFemaleSpinal CordNerve DegenerationMicrogliaMotor NeuronsGasdermins

MeSH Terms

PyroptosisSuperoxide Dismutase-1GasderminsAmyotrophic Lateral SclerosisAnimalsDisease Models, AnimalFemaleMaleMice, Inbred C57BLMice, TransgenicMotor NeuronsNerve DegenerationSpinal CordMicrogliaPhosphate-Binding ProteinsIntracellular Signaling Peptides and ProteinsMice

Keywords

NeurodegenerationPyroptosisNeuroscienceAmyotrophic lateral sclerosisBiologyMedicineInflammasomeInflammationImmunologyDiseaseCell deathMicrogliaNeuroimmunologyALSGasdermin D

Sustainable Development Goals

SDG 0: Zero hunger

Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis

FAIR Checklist

Authors (8)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)