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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice

Neuron(2020)10.1016/j.neuron.2020.03.005Source: DataRank Database

The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice is a research paper published in Neuron (2020). On theSindex it has a DataRank of 0. It has been cited 109 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access109 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 5.61)OA: bronzeTopics (47)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Esther Kaunga,Junqiang Ye ORCID,Daniele Canzio ORCID,Sean O’Keeffe ORCID,Noam D. Rudnick

Live enrichment

PubMed:32220666 OpenAlex:https://openalex.org/W3013449576

NIH HHS

Grant: U54 OD020351

NIGMS NIH HHS

Grant: K99 GM121815

Takeda Pharmaceuticals U.S.A.

Amyotrophic Lateral Sclerosis Association

FWCI

5.61

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.cell.com/article/S0896627320301914/pdf

publisherhttp://www.cell.com/article/S0896627320301914/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0896627320301914?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0896627320301914?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.neuron.2020.03.005

Fields of Study

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

MeSH Terms

Superoxide Dismutase-1Loss of Function MutationAmyotrophic Lateral SclerosisAnimalsAutophagyDisease Models, AnimalInflammationMotor NeuronsNeuromuscular JunctionSurvival RateProtein Serine-Threonine KinasesMicrogliaAge of OnsetMice, KnockoutDisease ProgressionMutation, MissenseMiceGene Knock-In Techniques

Keywords

TANK-binding kinase 1Amyotrophic lateral sclerosisNeurodegenerationSOD1BiologyLoss functionKinaseMotor neuronPhenotypeNeuroscienceGeneDiseaseCancer researchGeneticsProtein kinase AMedicineSpinal cordPathologyCyclin-dependent kinase 2ALSneuroinflammationGliaInterferon ResponseTbk1Selective AutophagySod1 Mouse ModelMotor Neuron Autophagy