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Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD

Neuron(2023)10.1016/j.neuron.2023.02.029Source: DataRank Database

Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD is a research paper published in Neuron (2023). On theSindex it has a DataRank of 0. It has been cited 27 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access27 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 4.25)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Yong‐Woo Jun ORCID,Gabriel Linares ORCID,Brandon Butler ORCID,Yeliz Yuva-Adyemir,Jill E. Moore ORCID

Live enrichment

PubMed:36931278 PMC:PMC10264157 OpenAlex:https://openalex.org/W4327576923

NINDS NIH HHS

Grant: R01 NS101986

NIAID NIH HHS

Grant: R01 AI060025

NINDS NIH HHS

Grant: R01 NS097850

NINDS NIH HHS

Grant: R37 NS057553

NINDS NIH HHS

Grant: R44 NS097094

NHGRI NIH HHS

Grant: U24 HG012343

NINDS NIH HHS

Grant: RF1 NS101986

NIH HHS

Grant: S10 OD021580

FWCI

4.25

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S0896627323001332/pdf

publisherhttp://www.cell.com/article/S0896627323001332/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0896627323001332?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0896627323001332?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.neuron.2023.02.029

Fields of Study

Amyotrophic Lateral Sclerosis ResearchCholinesterase and Neurodegenerative DiseasesCoenzyme Q10 studies and effects

MeSH Terms

C9orf72 ProteinAmyotrophic Lateral SclerosisAnimalsDipeptidesDisease Models, AnimalDrosophilaHeat-Shock ProteinsMotor NeuronsDown-RegulationAntimicrobial Cationic PeptidesDrosophila ProteinsDNA Repeat ExpansionFrontotemporal Dementia

Keywords

C9orf72Gene knockdownNeurodegenerationAmyotrophic lateral sclerosisDownregulation and upregulationNeurotoxicityInduced pluripotent stem cellBiologyHsp90Cell biologyHeat shock proteinTrinucleotide repeat expansionChemistryMolecular biologyGeneToxicityBiochemistryMedicineInternal medicineAntimicrobial peptideTOPOIIALSFtdDprMtkPoly(gr)

Sustainable Development Goals

SDG 0: Good health and well-being